Pre-made Sulesomab benchmark antibody (Radiolabelled antibody, anti-NCA-90 (nonspecific cross- reacting antigens 90kDa glycoproteins, granulocyte cell antigen) therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Pre-made Sulesomab benchmark antibody (Radiolabelled antibody, anti-NCA-90 (nonspecific cross- reacting antigens 90kDa glycoproteins, granulocyte cell antigen) therapeutic antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Technetium (99mTc) sulesomab (trade name LeukoScan) is a radio-pharmaceutical composed of anti-human mouse monoclonal antibody[1] that targets the granulocyte associated NCA-9 cell antigen and a conjugated technetium-99m radionuclide. After intravenous administration, Leukoscan enables sensitive and specific whole body measurement of granulocyte infiltration and activation by gamma camera imaging of 99mTc-antibody bound cells.[2] Total clearance of LeukoScan from blood samples after administration and imaging has been reported at 48 hour time points indicating limited retention of the agent in circulation[3]

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-1000-1mg	1mg	3090
GMP-Bios-INN-1000-10mg	10mg	Inquiry
GMP-Bios-INN-1000-100mg	100mg	Inquiry
GMP-Bios-INN-1000-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Sulesomab Biosimilar, Radiolabelled Antibody: Anti-Nca-90 (Nonspecific Cross- Reacting Antigens 90Kda Glycoproteins, Granulocyte Cell Antigen) therapeutic antibody
INN Name	Sulesomab
Target	NCA-90 (nonspecific cross- reacting antigens 90kDa glycoproteins, granulocyte cell antigen)
Format	Radiolabelled antibody
Derivation	Mus musculus
Species Reactivity	human
CH1 Isotype	Fab' - G1 - nd
VD LC	Fab' - G1 - nd
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	Immunomedics Inc. (Morris Plains NJ USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	0