ST8SIA1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of ST8SIA1. The page also collects GeneMedi's different modalities and formats products for ST8SIA1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ST8SIA1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]

Target IDGM-IP1835
Target NameST8SIA1
Gene ID6489,20449,25280,706707,477672,101093029,282352
Gene Symbol and Synonyms9330109E03Rik,GD3S,Sia-T,SIAT8,SIAT8-A,SIAT8A,ST8SIA1,ST8SiaI
Uniprot AccessionQ92185,Q6ZXD2
Uniprot Entry NameSIA8A_HUMAN,SIA8A_BOVIN
Protein Sub-locationIntrocelluar Protein
Category
DiseaseN/A
Gene EnsemblENSG00000111728
Target ClassificationN/A


Pre-made anti-ST8SIA1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-ST8SIA1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ST8SIA1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-ST8SIA1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabDetail



Recombinant multi-species SIA8A/ ST8SIA1/ GD3S protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ST8SIA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
ST8SIA1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made ST8SIA1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP001344human NM_003034humanNM_003034 Lentivirus particleNM_003034HumanLentivirus particleDetail
vGMLP003149human ST8SIA1 Lentivirus particleNM_003034HumanLentivirus particleDetail
vGMLV000269human ST8SIA1 Lentivirus particleNM_003034.3HumanLentivirus particleDetail
pGMLP003149human ST8SIA1 Lentivirus plasmidNM_003034HumanLentivirus plasmidDetail
pGMLP001344human NM_003034humanNM_003034 Lentivirus plasmidNM_003034HumanLentivirus plasmidDetail
pGMLV000269human ST8SIA1 Lentivirus plasmidNM_003034.3HumanLentivirus plasmidDetail
pGMLPm002906mouse St8sia1 Lentivirus plasmidNM_011374MouseLentivirus plasmidDetail
vGMLPm002906mouse St8sia1 Lentivirus particleNM_011374MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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