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Anti-ST8SIA1 monoclonal antibody
Pre-made anti-ST8SIA1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ST8SIA1/ST8SIA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1835-Ab-1/ GM-Tg-hg-IP1835-Ab-2 | Anti-Human ST8SIA1 monoclonal antibody | Human |
| GM-Tg-rg-IP1835-Ab-1/ GM-Tg-rg-IP1835-Ab-2 | Anti-Rat ST8SIA1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1835-Ab-1/ GM-Tg-mg-IP1835-Ab-2 | Anti-Mouse ST8SIA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1835-Ab-1/ GM-Tg-cynog-IP1835-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ST8SIA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1835-Ab-1/ GM-Tg-felg-IP1835-Ab-2 | Anti-Feline ST8SIA1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1835-Ab-1/ GM-Tg-cang-IP1835-Ab-2 | Anti-Canine ST8SIA1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1835-Ab-1/ GM-Tg-bovg-IP1835-Ab-2 | Anti-Bovine ST8SIA1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1835-Ab-1/ GM-Tg-equg-IP1835-Ab-2 | Anti-Equine ST8SIA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1835-Ab-1/ GM-Tg-hg-IP1835-Ab-2; GM-Tg-rg-IP1835-Ab-1/ GM-Tg-rg-IP1835-Ab-2; GM-Tg-mg-IP1835-Ab-1/ GM-Tg-mg-IP1835-Ab-2; GM-Tg-cynog-IP1835-Ab-1/ GM-Tg-cynog-IP1835-Ab-2; GM-Tg-felg-IP1835-Ab-1/ GM-Tg-felg-IP1835-Ab-2; GM-Tg-cang-IP1835-Ab-1/ GM-Tg-cang-IP1835-Ab-2; GM-Tg-bovg-IP1835-Ab-1/ GM-Tg-bovg-IP1835-Ab-2; GM-Tg-equg-IP1835-Ab-1/ GM-Tg-equg-IP1835-Ab-2 |
| Products Name | Anti-ST8SIA1 monoclonal antibody |
| Format | mab |
| Target Name | ST8SIA1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ST8SIA1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1835-Ag-1 | Recombinant multi-species SIA8A/ ST8SIA1/ GD3S protein |
| ORF Viral Vector | vGMLP001344 | human NM_003034humanNM_003034 Lentivirus particle |
| ORF Viral Vector | vGMLP003149 | human ST8SIA1 Lentivirus particle |
| ORF Viral Vector | vGMLV000269 | human ST8SIA1 Lentivirus particle |
| ORF Viral Vector | pGMLP003149 | human ST8SIA1 Lentivirus plasmid |
| ORF Viral Vector | pGMLP001344 | human NM_003034humanNM_003034 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000269 | human ST8SIA1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002906 | mouse St8sia1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002906 | mouse St8sia1 Lentivirus particle |
Target information
| Target ID | GM-IP1835 |
| Target Name | ST8SIA1 |
| Gene ID | 6489,20449,25280,706707,477672,101093029,282352 |
| Gene Symbol and Synonyms | 9330109E03Rik,GD3S,Sia-T,SIAT8,SIAT8-A,SIAT8A,ST8SIA1,ST8SiaI |
| Uniprot Accession | Q92185,Q6ZXD2 |
| Uniprot Entry Name | SIA8A_HUMAN,SIA8A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000111728 |
| Target Classification | N/A |
The target: ST8SIA1, gene name: ST8SIA1, also named as GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI. Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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