Potency Validated COVID-19 SARS-CoV-2 neutralizing antibody,Anti-2019-nCoV Spike (Spike RBD domain) human monoclonal neutralizing antibody (IgM)

GMP-V-2019nCoV-SnAb002

Order information

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)

GMP-V-2019nCoV-SnAb002-1mg

1mg 5090

GMP-V-2019nCoV-SnAb002-10mg

10mg 35890

GMP-V-2019nCoV-SnAb002-100mg

100mg 228090

GMP-V-2019nCoV-SnAb002-xmg

≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Expression platform human IgM
Isotypes Mammalian (human cell)
Products descriptionAnti-2019-nCoV Spike (Spike RBD domain) human monoclonal neutralizing antibody (IgM):

GMP-V-2019nCoV-SnAb002, is a potency validated COVID-19 SARS-CoV-2 neutralizing antibody.This This antibodies can either act as positive control in COVID-19 related vaccines and neutralizing antibodies discovery and development, or act as a benchmark in SARS-CoV-2 neutralization potency assay. GeneMedi's validated COVID-19 neutralizing antibodies group including:

GMP-V-2019nCoV-SnAb001(human IgG1),

GMP-V-2019nCoV-SnAb002(human IgM),

GMP-V-2019nCoV-SnAb003(human IGA),

GMP-V-2019nCoV-SnAb004(mouse IgG1),and

GMP-V-2019nCoV-SnAb005(Cynomolgus (Non human primate, NHP) IgG1).

Bioactivity validationValidated in COVID-19 Spike protein and Spike-RBD protein binding affnity. COVID-19 related neutralizing potency is validated by 1.2019nCoV pseudotyped virus based neutralization assay in 293T-ACE2 effector cell. 2. competitively blocking the binding of ACE-2 receptor with SARS-CoV-2 Spike protein.
PurityPurity: ≥95% (SDS-PAGE)
Applicationpositive control in COVID-19 related vaccines and neutralizing antibodies discovery, also act as a benchmark in SARS-CoV-2 neutralization potency assay.
Predicted Molecular Mass48.9&24.2kDa
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.