Human SOCS1/AISIMD/CIS1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_003745.2)

SKU: pGMPC001717
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SOCS1/AISIMD/CIS1 Non-Viral expression plasmid (overexpression vector) for mouse SOCS1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001717
Gene Name SOCS1
Accession Number NM_003745.2
Gene ID 8651
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 636 bp
Gene Alias AISIMD,CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP-3,TIP3
Fluorescent Reporter Null
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T06800-Ab Anti-SOCS1 monoclonal antibody
    Target Antigen GM-Tg-g-T06800-Ag SOCS1 protein
    ORF Viral Vector pGMLP003452 Human SOCS1 Lentivirus plasmid
    ORF Viral Vector pGMLV000858 Human SOCS1 Lentivirus plasmid
    ORF Viral Vector pGMPC000656 Human SOCS1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001717 Human SOCS1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP003452 Human SOCS1 Lentivirus particle
    ORF Viral Vector vGMLV000858 Human SOCS1 Lentivirus particle


    Target information

    Target ID GM-T06800
    Target Name SOCS1
    Gene ID 8651, 12703, 711180, 252971, 111558242, 490006, 518795, 102148488
    Gene Symbol and Synonyms AISIMD,CIS1,CISH1,Cish7,JAB,SOCS-1,SOCS1,SSI-1,SSI1,TIP-3,TIP3
    Uniprot Accession O15524
    Uniprot Entry Name SOCS1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000185338
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]



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