Diagnostics antibodies and antigens for Inflammation/autoimmune/inflammatory diseases

Inflammation/autoimmune/inflammatory diseases occur when the immune system attacks the normal tissue within joints, vasculature, and other organ systems, causing inflammation, pain, diminished mobility, fatigue, and other non-specific symptoms. The strong overlap of signs and symptoms among the autoimmune diseases can lead to delays in diagnosis and appropriate treatment. However, immunodiagnostics has been developed to detect the inflammation/autoimmune/inflammatory disease such as ankylosing spondylitis, bacterial infections, bacterial meningitis, cerebrovascular diseases, crohn's disease, fungal infection, graves' disease, inflammatory amyloidosis, inflammatory bowel disease, mog antibody disease, osteomyelitis, rheumatoid arthritis, sepsis, respiratory illnesses and so on at an early stage. Biomarkers have been developed to detect this autoimmune disease at an early stage. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

• Validation data
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GeneMedi's products validation

• IL-6 (Interleukin 6)
• PCT (procalcitonin)
• IFNγ

GeneMedi's IL-6 (Interleukin 6) Antibody Pair Validation In Sandwich ELISA

Figure. GeneMedi's IL-6 antibody pair validation with IL-6 antigen (IL-6-Ag01) in sandwich ELISA.

Abbreviation	Description
IL-6-Ab01	GMP-h-IL-6-Ab01
IL-6-Ab02	GMP-h-IL-6-Ab02
IL6-Ab03	GMP-h-IL6-Ab03
IL-6-Ag01	GMP-h-IL-6-Ag01

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GeneMedi's PCT (procalcitonin) Antibody Pair Validation In Sandwich ELISA

Figure. GeneMedi's PCT antibody pair validation with PCT antigen (PCT-Ag01) in sandwich ELISA.

Abbreviation	Description
PCT-Ab01	GMP-h-PCT-Ab01
PCT-Ab02	GMP-h-PCT-Ab02
PCT-Ag01	GMP-h-PCT-Ag01

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GeneMedi's IFNγ antibodies demonstrate superior performance in immunoassay

GeneMedi’s GMP-h-IFNγ-Ab03 and GMP-h-IFNγ-Ab04 antibodies demonstrate superior performance in sandwich ELISA assays compared to other commercial products. Their exceptional sensitivity is reflected in significantly lower EC50 values, indicating enhanced binding affinity and detection capability. These properties make them an excellent choice for applications requiring high precision and reliability in quantitative analysis, offering researchers greater confidence in their assay results.

Figure 1. GeneMedi’s GMP-h-IFNγ-Ab03 and GMP-h-IFNγ-Ab04 antibodies demonstrate superior performance in sandwich ELISA assays compared to other commercial products.

A.The binding curves of different GMP-h-IFNγ-Ab03 coating concentrations and GMP-h-IFNγ-Ab04 biotin detecting concentrations.
B-D. Sandwich ELISA assay using 0.5ug/ml (B), 1ug/ml (C), and 2ug/ml (D) capture antibody (GMP-h-IFNγ-Ab03) with different concentrations of the detection antibody (GMP-h-IFNγ-Ab04) biotin. The unique commercial antibody pair is used for Head-to-head comparation in this study.
E.The EC50 results of different GMP-h-IFNγ-Ab03 coating concentrations and GMP-h-IFNγ-Ab04 biotin detecting concentrations.

GeneMedi's products for Inflammation/autoimmune/inflammatory diseases