FTH1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of FTH1. The page also collects GeneMedi's different modalities and formats products for FTH1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the FTH1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Target IDGM-T89873
Target NameFTH1
Gene ID2495,14319,25319,574118,403631,654516,281173,100062811
Gene Symbol and SynonymsFHC,FTH,FTH1,FTHL6,HFE5,HFt,LOC403631,MFH,PIG15,PLIF
Uniprot AccessionP02794,P19132,Q2MHN2,O46414,Q8MIP0
Uniprot Entry NameFRIH_HUMAN,FRIH_RAT,FRIH_FELCA,FRIH_BOVIN,FRIH_HORSE
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000167996
Target ClassificationN/A


Pre-made anti-FTH1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-FTH1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FTH1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-FTH1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species FRIH/ FTH1/ FHC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FTH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
FTH1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made FTH1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMAP000151Human FTH1 Adenovirus plasmidBC000857HumanAdenovirus plasmidDetail
vGMLV000308human FTH1 Lentivirus particleNM_002032HumanLentivirus particleDetail
pGMLV000308human FTH1 Lentivirus plasmidNM_002032HumanLentivirus plasmidDetail
vGMLV000307human FTH1 Lentivirus particleNM_002032.2HumanLentivirus particleDetail
pGMLV000307human FTH1 Lentivirus plasmidNM_002032.2HumanLentivirus plasmidDetail
vGMAP000151Human FTH1 Adenovirus particleBC000857HumanAdenovirus particleDetail
pGMLV000151mouse Fth1 Lentivirus plasmidNM_010239.2MouseLentivirus plasmidDetail
pGMLV000760house mouse Fth1 Lentivirus plasmidNM_010239.2House MouseLentivirus plasmidDetail
vGMLV000151mouse Fth1 Lentivirus particleNM_010239.2MouseLentivirus particleDetail
vGMLV000760house mouse Fth1 Lentivirus particleNM_010239.2House MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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