FTH1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of FTH1. The page also collects GeneMedi's different modalities and formats products for FTH1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the FTH1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Target ID | GM-T89873 |
Target Name | FTH1 |
Gene ID | 2495,14319,25319,574118,403631,654516,281173,100062811 |
Gene Symbol and Synonyms | FHC,FTH,FTH1,FTHL6,HFE5,HFt,LOC403631,MFH,PIG15,PLIF |
Uniprot Accession | P02794,P19132,Q2MHN2,O46414,Q8MIP0 |
Uniprot Entry Name | FRIH_HUMAN,FRIH_RAT,FRIH_FELCA,FRIH_BOVIN,FRIH_HORSE |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000167996 |
Target Classification | N/A |
Pre-made anti-FTH1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-FTH1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FTH1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-FTH1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species FRIH/ FTH1/ FHC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FTH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
FTH1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made FTH1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMAP000151 | Human FTH1 Adenovirus plasmid | BC000857 | Human | Adenovirus plasmid | Detail |
vGMLV000308 | human FTH1 Lentivirus particle | NM_002032 | Human | Lentivirus particle | Detail |
pGMLV000308 | human FTH1 Lentivirus plasmid | NM_002032 | Human | Lentivirus plasmid | Detail |
vGMLV000307 | human FTH1 Lentivirus particle | NM_002032.2 | Human | Lentivirus particle | Detail |
pGMLV000307 | human FTH1 Lentivirus plasmid | NM_002032.2 | Human | Lentivirus plasmid | Detail |
vGMAP000151 | Human FTH1 Adenovirus particle | BC000857 | Human | Adenovirus particle | Detail |
pGMLV000151 | mouse Fth1 Lentivirus plasmid | NM_010239.2 | Mouse | Lentivirus plasmid | Detail |
pGMLV000760 | house mouse Fth1 Lentivirus plasmid | NM_010239.2 | House Mouse | Lentivirus plasmid | Detail |
vGMLV000151 | mouse Fth1 Lentivirus particle | NM_010239.2 | Mouse | Lentivirus particle | Detail |
vGMLV000760 | house mouse Fth1 Lentivirus particle | NM_010239.2 | House Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.