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Anti-FTH1 monoclonal antibody
Pre-made anti-FTH1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FTH1/FTH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T89873-Ab-1/ GM-Tg-hg-T89873-Ab-2 | Anti-Human FTH1 monoclonal antibody | Human |
| GM-Tg-rg-T89873-Ab-1/ GM-Tg-rg-T89873-Ab-2 | Anti-Rat FTH1 monoclonal antibody | Rat |
| GM-Tg-mg-T89873-Ab-1/ GM-Tg-mg-T89873-Ab-2 | Anti-Mouse FTH1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T89873-Ab-1/ GM-Tg-cynog-T89873-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FTH1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T89873-Ab-1/ GM-Tg-felg-T89873-Ab-2 | Anti-Feline FTH1 monoclonal antibody | Feline |
| GM-Tg-cang-T89873-Ab-1/ GM-Tg-cang-T89873-Ab-2 | Anti-Canine FTH1 monoclonal antibody | Canine |
| GM-Tg-bovg-T89873-Ab-1/ GM-Tg-bovg-T89873-Ab-2 | Anti-Bovine FTH1 monoclonal antibody | Bovine |
| GM-Tg-equg-T89873-Ab-1/ GM-Tg-equg-T89873-Ab-2 | Anti-Equine FTH1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T89873-Ab-1/ GM-Tg-hg-T89873-Ab-2; GM-Tg-rg-T89873-Ab-1/ GM-Tg-rg-T89873-Ab-2; GM-Tg-mg-T89873-Ab-1/ GM-Tg-mg-T89873-Ab-2; GM-Tg-cynog-T89873-Ab-1/ GM-Tg-cynog-T89873-Ab-2; GM-Tg-felg-T89873-Ab-1/ GM-Tg-felg-T89873-Ab-2; GM-Tg-cang-T89873-Ab-1/ GM-Tg-cang-T89873-Ab-2; GM-Tg-bovg-T89873-Ab-1/ GM-Tg-bovg-T89873-Ab-2; GM-Tg-equg-T89873-Ab-1/ GM-Tg-equg-T89873-Ab-2 |
| Products Name | Anti-FTH1 monoclonal antibody |
| Format | mab |
| Target Name | FTH1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FTH1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T89873-Ag-1 | Recombinant multi-species FRIH/ FTH1/ FHC protein |
| ORF Viral Vector | pGMAP000151 | Human FTH1 Adenovirus plasmid |
| ORF Viral Vector | vGMLV000308 | human FTH1 Lentivirus particle |
| ORF Viral Vector | pGMLV000308 | human FTH1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000307 | human FTH1 Lentivirus particle |
| ORF Viral Vector | pGMLV000307 | human FTH1 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000151 | Human FTH1 Adenovirus particle |
| ORF Viral Vector | pGMLV000151 | mouse Fth1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000760 | house mouse Fth1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000151 | mouse Fth1 Lentivirus particle |
| ORF Viral Vector | vGMLV000760 | house mouse Fth1 Lentivirus particle |
Target information
| Target ID | GM-T89873 |
| Target Name | FTH1 |
| Gene ID | 2495,14319,25319,574118,403631,654516,281173,100062811 |
| Gene Symbol and Synonyms | FHC,FTH,FTH1,FTHL6,HFE5,HFt,LOC403631,MFH,PIG15,PLIF |
| Uniprot Accession | P02794,P19132,Q2MHN2,O46414,Q8MIP0 |
| Uniprot Entry Name | FRIH_HUMAN,FRIH_RAT,FRIH_FELCA,FRIH_BOVIN,FRIH_HORSE |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000167996 |
| Target Classification | N/A |
The target: FTH1, gene name: FTH1, also named as FHC, FTH, FTHL6, HFE5, PIG15, PLIF. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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