ALDH3A1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of ALDH3A1. The page also collects GeneMedi's different modalities and formats products for ALDH3A1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ALDH3A1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Target IDGM-MP1982
Target NameALDH3A1
Gene ID218,11670,25375,703870,489526,101096364,281617,100073157
Gene Symbol and SynonymsAhd-4,Ahd-c,Ahd4,AHDC,Aldh,ALDH3,ALDH3A1,ALDHIII
Uniprot AccessionP30838,P11883,A3RF36,P30907
Uniprot Entry NameAL3A1_HUMAN,AL3A1_RAT,AL3A1_CANLF,AL3A1_BOVIN
Protein Sub-locationTransmembrane Protein
Category
DiseaseLung Cancer
Gene EnsemblENSG00000108602
Target ClassificationN/A


Pre-made anti-ALDH3A1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-ALDH3A1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ALDH3A1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-ALDH3A1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional AntibodyDetail



Multi-species AL3A1/ ALDH3A1/ ALDH3 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDH3A1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
ALDH3A1 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made ALDH3A1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLV000478human ALDH3A1 Lentivirus plasmidNM_001135168.1HumanLentivirus plasmidDetail
pGMLP003163human ALDH3A1 Lentivirus plasmidNM_000691HumanLentivirus plasmidDetail
vGMLV000478human ALDH3A1 Lentivirus particleNM_001135168.1HumanLentivirus particleDetail
vGMLP003163human ALDH3A1 Lentivirus particleNM_000691HumanLentivirus particleDetail
pGMLPm001779mouse Aldh3a1 Lentivirus plasmidNM_001331112MouseLentivirus plasmidDetail
vGMLPm001779mouse Aldh3a1 Lentivirus particleNM_001331112MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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