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Anti-AL3A1/ ALDH3A1/ ALDH3 monoclonal antibody
Anti-AL3A1/ ALDH3A1/ ALDH3 antibody for FACS & in-vivo assay
Go to ALDH3A1/ALDH3A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1982-Ab-1/ GM-Tg-hg-MP1982-Ab-2 | Anti-Human ALDH3A1 monoclonal antibody | Human |
| GM-Tg-rg-MP1982-Ab-1/ GM-Tg-rg-MP1982-Ab-2 | Anti-Rat ALDH3A1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1982-Ab-1/ GM-Tg-mg-MP1982-Ab-2 | Anti-Mouse ALDH3A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1982-Ab-1/ GM-Tg-cynog-MP1982-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ALDH3A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1982-Ab-1/ GM-Tg-felg-MP1982-Ab-2 | Anti-Feline ALDH3A1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1982-Ab-1/ GM-Tg-cang-MP1982-Ab-2 | Anti-Canine ALDH3A1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1982-Ab-1/ GM-Tg-bovg-MP1982-Ab-2 | Anti-Bovine ALDH3A1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1982-Ab-1/ GM-Tg-equg-MP1982-Ab-2 | Anti-Equine ALDH3A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1982-Ab-1/ GM-Tg-hg-MP1982-Ab-2; GM-Tg-rg-MP1982-Ab-1/ GM-Tg-rg-MP1982-Ab-2; GM-Tg-mg-MP1982-Ab-1/ GM-Tg-mg-MP1982-Ab-2; GM-Tg-cynog-MP1982-Ab-1/ GM-Tg-cynog-MP1982-Ab-2; GM-Tg-felg-MP1982-Ab-1/ GM-Tg-felg-MP1982-Ab-2; GM-Tg-cang-MP1982-Ab-1/ GM-Tg-cang-MP1982-Ab-2; GM-Tg-bovg-MP1982-Ab-1/ GM-Tg-bovg-MP1982-Ab-2; GM-Tg-equg-MP1982-Ab-1/ GM-Tg-equg-MP1982-Ab-2 |
| Products Name | Anti-ALDH3A1 monoclonal antibody |
| Format | mab |
| Target Name | ALDH3A1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ALDH3A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species AL3A1/ ALDH3A1/ ALDH3 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLV000478 | human ALDH3A1 Lentivirus plasmid |
| ORF Viral Vector | pGMLP003163 | human ALDH3A1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000478 | human ALDH3A1 Lentivirus particle |
| ORF Viral Vector | vGMLP003163 | human ALDH3A1 Lentivirus particle |
| ORF Viral Vector | pGMLPm001779 | mouse Aldh3a1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001779 | mouse Aldh3a1 Lentivirus particle |
Target information
| Target ID | GM-MP1982 |
| Target Name | ALDH3A1 |
| Gene ID | 218,11670,25375,703870,489526,101096364,281617,100073157 |
| Gene Symbol and Synonyms | Ahd-4,Ahd-c,Ahd4,AHDC,Aldh,ALDH3,ALDH3A1,ALDHIII |
| Uniprot Accession | P30838,P11883,A3RF36,P30907 |
| Uniprot Entry Name | AL3A1_HUMAN,AL3A1_RAT,AL3A1_CANLF,AL3A1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000108602 |
| Target Classification | N/A |
The target: ALDH3A1, gene name: ALDH3A1, also named as ALDH3, ALDHIII. Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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