EMP3: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of EMP3. The page also collects GeneMedi's different modalities and formats products for EMP3 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the EMP3 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Target ID | GM-MP0405 |
Target Name | EMP3 |
Gene ID | 2014,13732,81505,717867,484408,101088446,535273,100050794 |
Gene Symbol and Synonyms | EMP3,H-4,H4,HNMP-1,MI-35,YMP |
Uniprot Accession | P54852,Q9QYW5,Q58DR6 |
Uniprot Entry Name | EMP3_HUMAN,EMP3_RAT,EMP3_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000142227 |
Target Classification | N/A |
Pre-made anti-EMP3 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-EMP3 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-EMP3 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-EMP3 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species EMP3/ YMP VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EMP3 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
EMP3 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made EMP3 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLV000327 | human EMP3 Lentivirus plasmid | NM_001425 | Human | Lentivirus plasmid | Detail |
pGMLP001223 | human EMP3 Lentivirus plasmid | NM_001425 | Human | Lentivirus plasmid | Detail |
vGMLP001223 | human EMP3 Lentivirus particle | NM_001425 | Human | Lentivirus particle | Detail |
vGMLV000327 | human EMP3 Lentivirus particle | NM_001425 | Human | Lentivirus particle | Detail |
pGMLPm000987 | mouse Emp3 Lentivirus plasmid | NM_001146346.1 | Mouse | Lentivirus plasmid | Detail |
pGMLPm005390 | mouse Emp3 Lentivirus plasmid | NM_001146346.1 | Mouse | Lentivirus plasmid | Detail |
vGMLPm000987 | mouse Emp3 Lentivirus particle | NM_001146346.1 | Mouse | Lentivirus particle | Detail |
vGMLPm005390 | mouse Emp3 Lentivirus particle | NM_001146346.1 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.