Anti-EMP3/ YMP monoclonal antibody

Anti-EMP3/ YMP antibody for FACS & in-vivo assay

Target products collectionGo to EMP3/EMP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0405-Ab-1/ GM-Tg-hg-MP0405-Ab-2Anti-Human EMP3 monoclonal antibodyHuman
GM-Tg-rg-MP0405-Ab-1/ GM-Tg-rg-MP0405-Ab-2Anti-Rat EMP3 monoclonal antibodyRat
GM-Tg-mg-MP0405-Ab-1/ GM-Tg-mg-MP0405-Ab-2Anti-Mouse EMP3 monoclonal antibodyMouse
GM-Tg-cynog-MP0405-Ab-1/ GM-Tg-cynog-MP0405-Ab-2Anti-Cynomolgus/ Rhesus macaque EMP3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0405-Ab-1/ GM-Tg-felg-MP0405-Ab-2Anti-Feline EMP3 monoclonal antibodyFeline
GM-Tg-cang-MP0405-Ab-1/ GM-Tg-cang-MP0405-Ab-2Anti-Canine EMP3 monoclonal antibodyCanine
GM-Tg-bovg-MP0405-Ab-1/ GM-Tg-bovg-MP0405-Ab-2Anti-Bovine EMP3 monoclonal antibodyBovine
GM-Tg-equg-MP0405-Ab-1/ GM-Tg-equg-MP0405-Ab-2Anti-Equine EMP3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0405-Ab-1/ GM-Tg-hg-MP0405-Ab-2; GM-Tg-rg-MP0405-Ab-1/ GM-Tg-rg-MP0405-Ab-2;
GM-Tg-mg-MP0405-Ab-1/ GM-Tg-mg-MP0405-Ab-2; GM-Tg-cynog-MP0405-Ab-1/ GM-Tg-cynog-MP0405-Ab-2;
GM-Tg-felg-MP0405-Ab-1/ GM-Tg-felg-MP0405-Ab-2; GM-Tg-cang-MP0405-Ab-1/ GM-Tg-cang-MP0405-Ab-2;
GM-Tg-bovg-MP0405-Ab-1/ GM-Tg-bovg-MP0405-Ab-2; GM-Tg-equg-MP0405-Ab-1/ GM-Tg-equg-MP0405-Ab-2
Products NameAnti-EMP3 monoclonal antibody
Formatmab
Target NameEMP3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EMP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EMP3/ YMP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLV000327human EMP3 Lentivirus plasmid
    ORF Viral VectorpGMLP001223human EMP3 Lentivirus plasmid
    ORF Viral VectorvGMLP001223human EMP3 Lentivirus particle
    ORF Viral VectorvGMLV000327human EMP3 Lentivirus particle
    ORF Viral VectorpGMLPm000987mouse Emp3 Lentivirus plasmid
    ORF Viral VectorpGMLPm005390mouse Emp3 Lentivirus plasmid
    ORF Viral VectorvGMLPm000987mouse Emp3 Lentivirus particle
    ORF Viral VectorvGMLPm005390mouse Emp3 Lentivirus particle


    Target information

    Target IDGM-MP0405
    Target NameEMP3
    Gene ID2014,13732,81505,717867,484408,101088446,535273,100050794
    Gene Symbol and SynonymsEMP3,H-4,H4,HNMP-1,MI-35,YMP
    Uniprot AccessionP54852,Q9QYW5,Q58DR6
    Uniprot Entry NameEMP3_HUMAN,EMP3_RAT,EMP3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000142227
    Target ClassificationN/A

    The target: EMP3, gene name: EMP3, also named as YMP. The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.