Anti-EMP3/ YMP monoclonal antibody
Anti-EMP3/ YMP antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP0405-Ab-1/ GM-Tg-hg-MP0405-Ab-2 | Anti-Human EMP3 monoclonal antibody | Human |
GM-Tg-rg-MP0405-Ab-1/ GM-Tg-rg-MP0405-Ab-2 | Anti-Rat EMP3 monoclonal antibody | Rat |
GM-Tg-mg-MP0405-Ab-1/ GM-Tg-mg-MP0405-Ab-2 | Anti-Mouse EMP3 monoclonal antibody | Mouse |
GM-Tg-cynog-MP0405-Ab-1/ GM-Tg-cynog-MP0405-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EMP3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP0405-Ab-1/ GM-Tg-felg-MP0405-Ab-2 | Anti-Feline EMP3 monoclonal antibody | Feline |
GM-Tg-cang-MP0405-Ab-1/ GM-Tg-cang-MP0405-Ab-2 | Anti-Canine EMP3 monoclonal antibody | Canine |
GM-Tg-bovg-MP0405-Ab-1/ GM-Tg-bovg-MP0405-Ab-2 | Anti-Bovine EMP3 monoclonal antibody | Bovine |
GM-Tg-equg-MP0405-Ab-1/ GM-Tg-equg-MP0405-Ab-2 | Anti-Equine EMP3 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP0405-Ab-1/ GM-Tg-hg-MP0405-Ab-2; GM-Tg-rg-MP0405-Ab-1/ GM-Tg-rg-MP0405-Ab-2; GM-Tg-mg-MP0405-Ab-1/ GM-Tg-mg-MP0405-Ab-2; GM-Tg-cynog-MP0405-Ab-1/ GM-Tg-cynog-MP0405-Ab-2; GM-Tg-felg-MP0405-Ab-1/ GM-Tg-felg-MP0405-Ab-2; GM-Tg-cang-MP0405-Ab-1/ GM-Tg-cang-MP0405-Ab-2; GM-Tg-bovg-MP0405-Ab-1/ GM-Tg-bovg-MP0405-Ab-2; GM-Tg-equg-MP0405-Ab-1/ GM-Tg-equg-MP0405-Ab-2 |
Products Name | Anti-EMP3 monoclonal antibody |
Format | mab |
Target Name | EMP3 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-EMP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species EMP3/ YMP VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMLV000327 | human EMP3 Lentivirus plasmid |
ORF Viral Vector | pGMLP001223 | human EMP3 Lentivirus plasmid |
ORF Viral Vector | vGMLP001223 | human EMP3 Lentivirus particle |
ORF Viral Vector | vGMLV000327 | human EMP3 Lentivirus particle |
ORF Viral Vector | pGMLPm000987 | mouse Emp3 Lentivirus plasmid |
ORF Viral Vector | pGMLPm005390 | mouse Emp3 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000987 | mouse Emp3 Lentivirus particle |
ORF Viral Vector | vGMLPm005390 | mouse Emp3 Lentivirus particle |
Target information
Target ID | GM-MP0405 |
Target Name | EMP3 |
Gene ID | 2014,13732,81505,717867,484408,101088446,535273,100050794 |
Gene Symbol and Synonyms | EMP3,H-4,H4,HNMP-1,MI-35,YMP |
Uniprot Accession | P54852,Q9QYW5,Q58DR6 |
Uniprot Entry Name | EMP3_HUMAN,EMP3_RAT,EMP3_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000142227 |
Target Classification | N/A |
The target: EMP3, gene name: EMP3, also named as YMP. The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.