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Anti-MSI2 monoclonal antibody
Pre-made anti-MSI2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MSI2/MSI2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T35817-Ab-1/ GM-Tg-hg-T35817-Ab-2 | Anti-Human MSI2 monoclonal antibody | Human |
| GM-Tg-rg-T35817-Ab-1/ GM-Tg-rg-T35817-Ab-2 | Anti-Rat MSI2 monoclonal antibody | Rat |
| GM-Tg-mg-T35817-Ab-1/ GM-Tg-mg-T35817-Ab-2 | Anti-Mouse MSI2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T35817-Ab-1/ GM-Tg-cynog-T35817-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MSI2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T35817-Ab-1/ GM-Tg-felg-T35817-Ab-2 | Anti-Feline MSI2 monoclonal antibody | Feline |
| GM-Tg-cang-T35817-Ab-1/ GM-Tg-cang-T35817-Ab-2 | Anti-Canine MSI2 monoclonal antibody | Canine |
| GM-Tg-bovg-T35817-Ab-1/ GM-Tg-bovg-T35817-Ab-2 | Anti-Bovine MSI2 monoclonal antibody | Bovine |
| GM-Tg-equg-T35817-Ab-1/ GM-Tg-equg-T35817-Ab-2 | Anti-Equine MSI2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T35817-Ab-1/ GM-Tg-hg-T35817-Ab-2; GM-Tg-rg-T35817-Ab-1/ GM-Tg-rg-T35817-Ab-2; GM-Tg-mg-T35817-Ab-1/ GM-Tg-mg-T35817-Ab-2; GM-Tg-cynog-T35817-Ab-1/ GM-Tg-cynog-T35817-Ab-2; GM-Tg-felg-T35817-Ab-1/ GM-Tg-felg-T35817-Ab-2; GM-Tg-cang-T35817-Ab-1/ GM-Tg-cang-T35817-Ab-2; GM-Tg-bovg-T35817-Ab-1/ GM-Tg-bovg-T35817-Ab-2; GM-Tg-equg-T35817-Ab-1/ GM-Tg-equg-T35817-Ab-2 |
| Products Name | Anti-MSI2 monoclonal antibody |
| Format | mab |
| Target Name | MSI2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MSI2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T35817-Ag-1 | Recombinant multi-species MSI2H/ MSI2 protein |
| ORF Viral Vector | vGMAP000181 | Human MSI2 Adenovirus particle |
| ORF Viral Vector | pGMLV000033 | human MSI2 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000033 | human MSI2 Lentivirus particle |
| ORF Viral Vector | pGMAP000181 | Human MSI2 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm001424 | mouse Msi2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001424 | mouse Msi2 Lentivirus particle |
Target information
| Target ID | GM-T35817 |
| Target Name | MSI2 |
| Gene ID | 124540,76626,360596,100423536,475148,101084147,505542,100070744 |
| Gene Symbol and Synonyms | 1700105C15Rik,MSI2,MSI2H,RGD1560397 |
| Uniprot Accession | Q96DH6 |
| Uniprot Entry Name | MSI2H_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000153944 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: MSI2, gene name: MSI2, also named as MSI2H. This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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