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Anti-CCL23/ CK-BETA-8/ CKb8 functional antibody
Anti-CCL23/ CK-BETA-8/ CKb8 functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL23/CCL23 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T23934-Ab-1/ GM-Tg-hg-T23934-Ab-2 | Anti-Human CCL23 monoclonal antibody | Human |
| GM-Tg-rg-T23934-Ab-1/ GM-Tg-rg-T23934-Ab-2 | Anti-Rat CCL23 monoclonal antibody | Rat |
| GM-Tg-mg-T23934-Ab-1/ GM-Tg-mg-T23934-Ab-2 | Anti-Mouse CCL23 monoclonal antibody | Mouse |
| GM-Tg-cynog-T23934-Ab-1/ GM-Tg-cynog-T23934-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL23 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T23934-Ab-1/ GM-Tg-felg-T23934-Ab-2 | Anti-Feline CCL23 monoclonal antibody | Feline |
| GM-Tg-cang-T23934-Ab-1/ GM-Tg-cang-T23934-Ab-2 | Anti-Canine CCL23 monoclonal antibody | Canine |
| GM-Tg-bovg-T23934-Ab-1/ GM-Tg-bovg-T23934-Ab-2 | Anti-Bovine CCL23 monoclonal antibody | Bovine |
| GM-Tg-equg-T23934-Ab-1/ GM-Tg-equg-T23934-Ab-2 | Anti-Equine CCL23 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T23934-Ab-1/ GM-Tg-hg-T23934-Ab-2; GM-Tg-rg-T23934-Ab-1/ GM-Tg-rg-T23934-Ab-2; GM-Tg-mg-T23934-Ab-1/ GM-Tg-mg-T23934-Ab-2; GM-Tg-cynog-T23934-Ab-1/ GM-Tg-cynog-T23934-Ab-2; GM-Tg-felg-T23934-Ab-1/ GM-Tg-felg-T23934-Ab-2; GM-Tg-cang-T23934-Ab-1/ GM-Tg-cang-T23934-Ab-2; GM-Tg-bovg-T23934-Ab-1/ GM-Tg-bovg-T23934-Ab-2; GM-Tg-equg-T23934-Ab-1/ GM-Tg-equg-T23934-Ab-2 |
| Products Name | Anti-CCL23 monoclonal antibody |
| Format | mab |
| Target Name | CCL23 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL23 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T23934-Ag-1 | Recombinant multi-species CCL23/ CK-BETA-8/ CKb8 protein |
| Cytokine | GM-Tg-g-T23934-Ag-1 | chemokine (C-C motif) ligand 23 (CCL23) protein |
| ORF Viral Vector | vGMLP004762 | human CCL23 Lentivirus particle |
| ORF Viral Vector | pGMLP004762 | human CCL23 Lentivirus plasmid |
Target information
| Target ID | GM-T23934 |
| Target Name | CCL23 |
| Gene ID | 6368 |
| Gene Symbol and Synonyms | CCL23,CK-BETA-8,Ckb-8,Ckb-8-1,CKb8,hmrp-2a,MIP-3,MIP3,MPIF-1,SCYA23 |
| Uniprot Accession | P55773 |
| Uniprot Entry Name | CCL23_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000274736 |
| Target Classification | N/A |
The target: CCL23, gene name: CCL23, also named as CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23, hmrp-2a. This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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