Human CCL23/CK-BETA-8/Ckb-8 ORF/cDNA clone-Lentivirus particle (NM_145898)

Cat. No.: vGMLP004762

Pre-made Human CCL23/CK-BETA-8/Ckb-8 Lentiviral expression plasmid for CCL23 lentivirus packaging, CCL23 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP004762 Human CCL23 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP004762
Gene Name CCL23
Accession Number NM_145898
Gene ID 6368
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 363 bp
Gene Alias CK-BETA-8,Ckb-8,Ckb-8-1,CKb8,hmrp-2a,MIP-3,MIP3,MPIF-1,SCYA23
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGGTCTCCGTGGCTGCCCTCTCCTGCCTCATGCTTGTTACTGCCCTTGGATCCCAGGCCCGGGTCACAAAAGATGCAGAGACAGAGTTCATGATGTCAAAGCTTCCATTGGAAAATCCAGTACTTCTGGACAGATTCCATGCTACTAGTGCTGACTGCTGCATCTCCTACACCCCACGAAGCATCCCGTGTTCACTCCTGGAGAGTTACTTTGAAACGAACAGCGAGTGCTCCAAGCCGGGTGTCATCTTCCTCACCAAGAAGGGGCGACGTTTCTGTGCCAACCCCAGTGATAAGCAAGTTCAGGTTTGCATGAGAATGCTGAAGCTGGACACACGGATCAAGACCAGGAAGAATTGA
ORF Protein Sequence MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T23934-Ab Anti-CCL23/ CK-BETA-8/ CKb8 functional antibody
    Target Antigen GM-Tg-g-T23934-Ag CCL23 protein
    Cytokine cks-Tg-g-GM-T23934 chemokine (C-C motif) ligand 23 (CCL23) protein & antibody
    ORF Viral Vector pGMLP004762 Human CCL23 Lentivirus plasmid
    ORF Viral Vector vGMLP004762 Human CCL23 Lentivirus particle


    Target information

    Target ID GM-T23934
    Target Name CCL23
    Gene ID 6368
    Gene Symbol and Synonyms CCL23,CK-BETA-8,Ckb-8,Ckb-8-1,CKb8,hmrp-2a,MIP-3,MIP3,MPIF-1,SCYA23
    Uniprot Accession P55773
    Uniprot Entry Name CCL23_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000274736
    Target Classification Not Available

    This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]



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