Anti-CD79B/ AGM6/ B29 monoclonal antibody

Anti-CD79B/ AGM6/ B29 antibody for FACS & in-vivo assay

Target products collectionGo to CD79B/CD79B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T08306-Ab-1/ GM-Tg-hg-T08306-Ab-2Anti-Human CD79B monoclonal antibodyHuman
GM-Tg-rg-T08306-Ab-1/ GM-Tg-rg-T08306-Ab-2Anti-Rat CD79B monoclonal antibodyRat
GM-Tg-mg-T08306-Ab-1/ GM-Tg-mg-T08306-Ab-2Anti-Mouse CD79B monoclonal antibodyMouse
GM-Tg-cynog-T08306-Ab-1/ GM-Tg-cynog-T08306-Ab-2Anti-Cynomolgus/ Rhesus macaque CD79B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T08306-Ab-1/ GM-Tg-felg-T08306-Ab-2Anti-Feline CD79B monoclonal antibodyFeline
GM-Tg-cang-T08306-Ab-1/ GM-Tg-cang-T08306-Ab-2Anti-Canine CD79B monoclonal antibodyCanine
GM-Tg-bovg-T08306-Ab-1/ GM-Tg-bovg-T08306-Ab-2Anti-Bovine CD79B monoclonal antibodyBovine
GM-Tg-equg-T08306-Ab-1/ GM-Tg-equg-T08306-Ab-2Anti-Equine CD79B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T08306-Ab-1/ GM-Tg-hg-T08306-Ab-2; GM-Tg-rg-T08306-Ab-1/ GM-Tg-rg-T08306-Ab-2;
GM-Tg-mg-T08306-Ab-1/ GM-Tg-mg-T08306-Ab-2; GM-Tg-cynog-T08306-Ab-1/ GM-Tg-cynog-T08306-Ab-2;
GM-Tg-felg-T08306-Ab-1/ GM-Tg-felg-T08306-Ab-2; GM-Tg-cang-T08306-Ab-1/ GM-Tg-cang-T08306-Ab-2;
GM-Tg-bovg-T08306-Ab-1/ GM-Tg-bovg-T08306-Ab-2; GM-Tg-equg-T08306-Ab-1/ GM-Tg-equg-T08306-Ab-2
Products NameAnti-CD79B monoclonal antibody
Formatmab
Target NameCD79B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CD79B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    BiosimilarGMP-Bios-INN-962Pre-Made Polatuzumab Vedotin Biosimilar, Whole Mab Adc, Anti-Cd79B Antibody: Anti-AGM6/B29/IGB therapeutic antibody Drug Conjugate
    BiosimilarGMP-Bios-INN-862Pre-Made Iladatuzumab Vedotin Biosimilar, Whole Mab Adc, Anti-Cd79B Antibody: Anti-AGM6/B29/IGB therapeutic antibody Drug Conjugate
    BiosimilarGMP-Bios-ab-264Pre-Made Iladatuzumab biosimilar, Whole mAb ADC, Anti-CD79B Antibody: Anti-AGM6/B29/IGB therapeutic antibody
    BiosimilarGMP-Bios-ab-449Pre-Made Polatuzumab biosimilar, Whole mAb ADC, Anti-CD79B Antibody: Anti-AGM6/B29/IGB therapeutic antibody
    Target AntigenProducts DevelopingMulti-species CD79B/ AGM6/ B29 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000751human CD79B Lentivirus particle
    ORF Viral VectorpGMLP000751human CD79B Lentivirus plasmid


    Target information

    Target IDGM-T08306
    Target NameCD79B
    Gene ID974,15985,171055,718218,609449,101098098,509801,100064460
    Gene Symbol and SynonymsAGM6,B29,CD79B,Ig-beta,IGB,Igbeta
    Uniprot AccessionP40259
    Uniprot Entry NameCD79B_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, INN Index
    DiseaseCancer
    Gene EnsemblENSG00000007312
    Target ClassificationTumor-associated antigen (TAA)

    The target: CD79B, gene name: CD79B, also named as AGM6, B29, IGB. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.