Anti-CCL26/ IMAC/ MIP-4a functional antibody

Anti-CCL26/ IMAC/ MIP-4a functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CCL26/CCL26 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0746-Ab-1/ GM-Tg-hg-SE0746-Ab-2Anti-Human CCL26 monoclonal antibodyHuman
GM-Tg-rg-SE0746-Ab-1/ GM-Tg-rg-SE0746-Ab-2Anti-Rat CCL26 monoclonal antibodyRat
GM-Tg-mg-SE0746-Ab-1/ GM-Tg-mg-SE0746-Ab-2Anti-Mouse CCL26 monoclonal antibodyMouse
GM-Tg-cynog-SE0746-Ab-1/ GM-Tg-cynog-SE0746-Ab-2Anti-Cynomolgus/ Rhesus macaque CCL26 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0746-Ab-1/ GM-Tg-felg-SE0746-Ab-2Anti-Feline CCL26 monoclonal antibodyFeline
GM-Tg-cang-SE0746-Ab-1/ GM-Tg-cang-SE0746-Ab-2Anti-Canine CCL26 monoclonal antibodyCanine
GM-Tg-bovg-SE0746-Ab-1/ GM-Tg-bovg-SE0746-Ab-2Anti-Bovine CCL26 monoclonal antibodyBovine
GM-Tg-equg-SE0746-Ab-1/ GM-Tg-equg-SE0746-Ab-2Anti-Equine CCL26 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0746-Ab-1/ GM-Tg-hg-SE0746-Ab-2; GM-Tg-rg-SE0746-Ab-1/ GM-Tg-rg-SE0746-Ab-2;
GM-Tg-mg-SE0746-Ab-1/ GM-Tg-mg-SE0746-Ab-2; GM-Tg-cynog-SE0746-Ab-1/ GM-Tg-cynog-SE0746-Ab-2;
GM-Tg-felg-SE0746-Ab-1/ GM-Tg-felg-SE0746-Ab-2; GM-Tg-cang-SE0746-Ab-1/ GM-Tg-cang-SE0746-Ab-2;
GM-Tg-bovg-SE0746-Ab-1/ GM-Tg-bovg-SE0746-Ab-2; GM-Tg-equg-SE0746-Ab-1/ GM-Tg-equg-SE0746-Ab-2
Products NameAnti-CCL26 monoclonal antibody
Formatmab
Target NameCCL26
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CCL26 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0746-Ag-1Recombinant multi-species CCL26/ IMAC/ MIP-4a protein
    CytokineGM-Tg-g-SE0746-Ag-1chemokine (C-C motif) ligand 26 (CCL26) protein
    ORF Viral VectorpGMLP000836human CCL26 Lentivirus plasmid
    ORF Viral VectorvGMLP000836human CCL26 Lentivirus particle
    ORF Viral VectorpGMLPm004546mouse Ccl26 Lentivirus plasmid
    ORF Viral VectorvGMLPm004546mouse Ccl26 Lentivirus particle


    Target information

    Target IDGM-SE0746
    Target NameCCL26
    Gene ID10344,541307,685958,716099,448789,101086525,508387,100630602
    Gene Symbol and SynonymsCCL26,Ccl26l,IMAC,MIP-4a,MIP-4alpha,SCYA26,TSC-1
    Uniprot AccessionQ9Y258,Q64H35
    Uniprot Entry NameCCL26_HUMAN,CCL26_CANLF
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseBreast Cancer
    Gene EnsemblENSG00000006606
    Target ClassificationN/A

    The target: CCL26, gene name: CCL26, also named as IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1. This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2020].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.