Anti-MESD/ BOCAC2 monoclonal antibody

Anti-MESD/ BOCAC2 antibody for FACS & in-vivo assay

Target products collectionGo to MESD/MESD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2585-Ab-1/ GM-Tg-hg-MP2585-Ab-2Anti-Human MESD monoclonal antibodyHuman
GM-Tg-rg-MP2585-Ab-1/ GM-Tg-rg-MP2585-Ab-2Anti-Rat MESD monoclonal antibodyRat
GM-Tg-mg-MP2585-Ab-1/ GM-Tg-mg-MP2585-Ab-2Anti-Mouse MESD monoclonal antibodyMouse
GM-Tg-cynog-MP2585-Ab-1/ GM-Tg-cynog-MP2585-Ab-2Anti-Cynomolgus/ Rhesus macaque MESD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2585-Ab-1/ GM-Tg-felg-MP2585-Ab-2Anti-Feline MESD monoclonal antibodyFeline
GM-Tg-cang-MP2585-Ab-1/ GM-Tg-cang-MP2585-Ab-2Anti-Canine MESD monoclonal antibodyCanine
GM-Tg-bovg-MP2585-Ab-1/ GM-Tg-bovg-MP2585-Ab-2Anti-Bovine MESD monoclonal antibodyBovine
GM-Tg-equg-MP2585-Ab-1/ GM-Tg-equg-MP2585-Ab-2Anti-Equine MESD monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2585-Ab-1/ GM-Tg-hg-MP2585-Ab-2; GM-Tg-rg-MP2585-Ab-1/ GM-Tg-rg-MP2585-Ab-2;
GM-Tg-mg-MP2585-Ab-1/ GM-Tg-mg-MP2585-Ab-2; GM-Tg-cynog-MP2585-Ab-1/ GM-Tg-cynog-MP2585-Ab-2;
GM-Tg-felg-MP2585-Ab-1/ GM-Tg-felg-MP2585-Ab-2; GM-Tg-cang-MP2585-Ab-1/ GM-Tg-cang-MP2585-Ab-2;
GM-Tg-bovg-MP2585-Ab-1/ GM-Tg-bovg-MP2585-Ab-2; GM-Tg-equg-MP2585-Ab-1/ GM-Tg-equg-MP2585-Ab-2
Products NameAnti-MESD monoclonal antibody
Formatmab
Target NameMESD
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MESD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MESD/ BOCAC2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003470human MESD Lentivirus particle
    ORF Viral VectorpGMLP000952human MESD Lentivirus plasmid
    ORF Viral VectorvGMLP000952human MESD Lentivirus particle
    ORF Viral VectorpGMLP003470human MESD Lentivirus plasmid
    ORF Viral VectorpGMLPm001062mouse Mesd Lentivirus plasmid
    ORF Viral VectorvGMLPm001062mouse Mesd Lentivirus particle


    Target information

    Target IDGM-MP2585
    Target NameMESD
    Gene ID23184,67943,308796,712993,488765,101094422,514610,100067329
    Gene Symbol and Synonyms2210015O11Rik,BOCA,MESD,MESDC2,mKIAA0081,msd,OI20
    Uniprot AccessionQ14696,Q5U2R7,Q3T0U1
    Uniprot Entry NameMESD_HUMAN,MESD_RAT,MESD_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000117899
    Target ClassificationN/A

    The target: MESD, gene name: MESD, also named as BOCAC2, MESD. Predicted to enable low-density lipoprotein particle receptor binding activity. Involved in ossification and protein folding. Located in endoplasmic reticulum. Implicated in osteogenesis imperfecta type 20. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.