Human IL36G/IL-1F9/IL-1H1 ORF/cDNA clone-Lentivirus particle (NM_019618)
Cat. No.: vGMLP003211
Pre-made Human IL36G/IL-1F9/IL-1H1 Lentiviral expression plasmid for IL36G lentivirus packaging, IL36G lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP003211 | Human IL36G Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP003211 |
Gene Name | IL36G |
Accession Number | NM_019618 |
Gene ID | 56300 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 510 bp |
Gene Alias | IL-1F9,IL-1H1,IL-1RP2,IL1E,IL1F9,IL1H1,IL1RP2 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGAGAGGCACTCCAGGAGACGCTGATGGTGGAGGAAGGGCCGTCTATCAATCAATGTGTAAACCTATTACTGGGACTATTAATGATTTGAATCAGCAAGTGTGGACCCTTCAGGGTCAGAACCTTGTGGCAGTTCCACGAAGTGACAGTGTGACCCCAGTCACTGTTGCTGTTATCACATGCAAGTATCCAGAGGCTCTTGAGCAAGGCAGAGGGGATCCCATTTATTTGGGAATCCAGAATCCAGAAATGTGTTTGTATTGTGAGAAGGTTGGAGAACAGCCCACATTGCAGCTAAAAGAGCAGAAGATCATGGATCTGTATGGCCAACCCGAGCCCGTGAAACCCTTCCTTTTCTACCGTGCCAAGACTGGTAGGACCTCCACCCTTGAGTCTGTGGCCTTCCCGGACTGGTTCATTGCCTCCTCCAAGAGAGACCAGCCCATCATTCTGACTTCAGAACTTGGGAAGTCATACAACACTGCCTTTGAATTAAATATAAATGACTGA |
ORF Protein Sequence | MRGTPGDADGGGRAVYQSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVITCKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFIASSKRDQPIILTSELGKSYNTAFELNIND |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T72514-Ab | Anti-IL36G/ IL-1F9/ IL-1H1 monoclonal antibody |
Target Antigen | GM-Tg-g-T72514-Ag | IL36G VLP (virus-like particle) |
Cytokine | cks-Tg-g-GM-T72514 | interleukin 36, gamma (IL36G) protein & antibody |
ORF Viral Vector | pGMLP003211 | Human IL36G Lentivirus plasmid |
ORF Viral Vector | pGMLP-IL-041 | Human IL36G Lentivirus plasmid |
ORF Viral Vector | pGMAP-IL-124 | Human IL36G Adenovirus plasmid |
ORF Viral Vector | vGMLP003211 | Human IL36G Lentivirus particle |
ORF Viral Vector | vGMLP-IL-041 | Human IL36G Lentivirus particle |
ORF Viral Vector | vGMAP-IL-124 | Human IL36G Adenovirus particle |
Target information
Target ID | GM-T72514 |
Target Name | IL36G |
Gene ID | 56300, 215257, 700822, 499744, 101081377, 100686137, 615762 |
Gene Symbol and Synonyms | If36g,IL-1F9,IL-1H1,IL-1RP2,IL-36gamma,IL1E,IL1F9,IL1H1,IL1RP2,IL36G,RGD1563019 |
Uniprot Accession | Q9NZH8 |
Uniprot Entry Name | IL36G_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Cytokine Target |
Disease | Not Available |
Gene Ensembl | ENSG00000136688 |
Target Classification | Not Available |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, May 2019]
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