Human HDAC8/CDA07/CDLS5 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_018486.3)

SKU: pGMPC001578
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HDAC8/CDA07/CDLS5 Non-Viral expression plasmid (overexpression vector) for mouse HDAC8 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001578
Gene Name HDAC8
Accession Number NM_018486.3
Gene ID 55869
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1134 bp
Gene Alias CDA07,CDLS5,HD8,HDACL1,KDAC8,MRXS6,RPD3,WTS
Fluorescent Reporter mCherry
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T28887-Ab Anti-HDAC8/ CDA07/ CDLS5 monoclonal antibody
    Target Antigen GM-Tg-g-T28887-Ag HDAC8 VLP (virus-like particle)
    ORF Viral Vector pGMLP001200 Human HDAC8 Lentivirus plasmid
    ORF Viral Vector pGMPC001578 Human HDAC8 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001200 Human HDAC8 Lentivirus particle


    Target information

    Target ID GM-T28887
    Target Name HDAC8
    Gene ID 55869, 70315, 699642, 363481, 101096383, 480957, 540666, 100052401
    Gene Symbol and Synonyms 2610007D20Rik,CDA07,CDLS5,HD8,HDAC8,HDACL1,KDAC8,MRXS6,RGD1562895,RPD3,WTS
    Uniprot Accession Q9BY41
    Uniprot Entry Name HDAC8_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000147099
    Target Classification Not Available

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.