Human SLC10A1/FHCA2/NTCP ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_003049)

Cat. No.: pGMPC000986
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SLC10A1/FHCA2/NTCP Non-Viral expression plasmid (overexpression vector) for mouse SLC10A1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000986
Gene Name SLC10A1
Accession Number NM_003049
Gene ID 6554
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1050 bp
Gene Alias FHCA2,NTCP
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T99189-Ab Anti-NTCP/ SLC10A1 monoclonal antibody
    Target Antigen GM-Tg-g-T99189-Ag SLC10A1 VLP (virus-like particle)
    ORF Viral Vector pGMLV000268 Human SLC10A1 Lentivirus plasmid
    ORF Viral Vector pGMLV000922 Human SLC10A1 Lentivirus plasmid
    ORF Viral Vector pGMLV001757 Human SLC10A1 Lentivirus plasmid
    ORF Viral Vector pGMLV002355 Human SLC10A1 Lentivirus plasmid
    ORF Viral Vector pGMAP000375 Human SLC10A1 Adenovirus plasmid
    ORF Viral Vector pGMPC000986 Human SLC10A1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000268 Human SLC10A1 Lentivirus particle
    ORF Viral Vector vGMLV000922 Human SLC10A1 Lentivirus particle
    ORF Viral Vector vGMLV001757 Human SLC10A1 Lentivirus particle
    ORF Viral Vector vGMLV002355 Human SLC10A1 Lentivirus particle
    ORF Viral Vector vGMAP000375 Human SLC10A1 Adenovirus particle


    Target information

    Target ID GM-T99189
    Target Name SLC10A1
    Gene ID 6554, 20493, 712925, 24777, 101080544, 480372, 532890, 100064290
    Gene Symbol and Synonyms FHCA2,NTCP,Ntcp1,SBACT,SLC10A1
    Uniprot Accession Q14973
    Uniprot Entry Name NTCP_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000100652
    Target Classification Not Available

    The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]



    About GMVC

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