Human SLC7A11/CCBR1/xCT ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_014331)

SKU: pGMPC000954
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SLC7A11/CCBR1/xCT Non-Viral expression plasmid (overexpression vector) for mouse SLC7A11 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000954
Gene Name SLC7A11
Accession Number NM_014331
Gene ID 23657
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1506 bp
Gene Alias CCBR1,xCT
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag MYC (C-Terminal)
Promoter EF1
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T11615-Ab Anti-XCT/ SLC7A11/ CCBR1 monoclonal antibody
    Target Antigen GM-Tg-g-T11615-Ag SLC7A11 VLP (virus-like particle)
    ORF Viral Vector pGMLP002698 Human SLC7A11 Lentivirus plasmid
    ORF Viral Vector pGMLV000645 Human SLC7A11 Lentivirus plasmid
    ORF Viral Vector pGMLV002270 Human SLC7A11 Lentivirus plasmid
    ORF Viral Vector pGMLV002421 Human SLC7A11 Lentivirus plasmid
    ORF Viral Vector pGMAD000772 Human SLC7A11 Adenovirus plasmid
    ORF Viral Vector pGMPC000851 Human SLC7A11 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000895 Human SLC7A11 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000954 Human SLC7A11 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002698 Human SLC7A11 Lentivirus particle
    ORF Viral Vector vGMLV000645 Human SLC7A11 Lentivirus particle
    ORF Viral Vector vGMLV002270 Human SLC7A11 Lentivirus particle
    ORF Viral Vector vGMLV002421 Human SLC7A11 Lentivirus particle
    ORF Viral Vector vGMAD000772 Human SLC7A11 Adenovirus particle


    Target information

    Target ID GM-T11615
    Target Name SLC7A11
    Gene ID 23657, 26570, 696516, 310392, 101099374, 483821, 524078, 100063433
    Gene Symbol and Synonyms 9930009M05Rik,CCBR1,SLC7A11,sut,xCT
    Uniprot Accession Q9UPY5
    Uniprot Entry Name XCT_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000151012
    Target Classification Not Available

    This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.