Human PCNA/ATLD2 ORF/cDNA clone-Lentivirus plasmid (NM_002592)

Cat. No.: pGMLV000502
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PCNA/ATLD2 Lentiviral expression plasmid for PCNA lentivirus packaging, PCNA lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000502
Gene Name PCNA
Accession Number NM_002592
Gene ID 5111
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 786 bp
Gene Alias ATLD2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T21782-Ab Anti-PCNA monoclonal antibody
    Target Antigen GM-Tg-g-T21782-Ag PCNA protein
    ORF Viral Vector pGMLV000281 Human PCNA Lentivirus plasmid
    ORF Viral Vector pGMLV000502 Human PCNA Lentivirus plasmid
    ORF Viral Vector pGMAP000111 Human PCNA Adenovirus plasmid
    ORF Viral Vector vGMLV000281 Human PCNA Lentivirus particle
    ORF Viral Vector vGMLV000502 Human PCNA Lentivirus particle
    ORF Viral Vector vGMAP000111 Human PCNA Adenovirus particle


    Target information

    Target ID GM-T21782
    Target Name PCNA
    Gene ID 5111, 18538, 718006, 25737, 101080704, 477166, 515499, 100052065
    Gene Symbol and Synonyms ATLD2,PCNA,Pcna/cyclin,PCNAR
    Uniprot Accession P12004
    Uniprot Entry Name PCNA_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Aggressive angiomyxoma (AAM), breast cancer, Proliferation and growth regulation
    Gene Ensembl ENSG00000132646
    Target Classification Not Available

    The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.