Human TIMP1/CLGI/EPA ORF/cDNA clone-Lentivirus plasmid (NM_003254.2)

Cat. No.: pGMLV000257
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TIMP1/CLGI/EPA Lentiviral expression plasmid for TIMP1 lentivirus packaging, TIMP1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000257
Gene Name TIMP1
Accession Number NM_003254.2
Gene ID 7076
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 624 bp
Gene Alias CLGI,EPA,EPO,HCI,TIMP,TIMP-1
Fluorescent Reporter ZsGreen-Firefly luciferase
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0506-Ab Anti-TIMP1/ CLGI/ EPA functional antibody
    Target Antigen GM-Tg-g-SE0506-Ag TIMP1 protein
    ORF Viral Vector pGMLP001347 Human TIMP1 Lentivirus plasmid
    ORF Viral Vector pGMLV000257 Human TIMP1 Lentivirus plasmid
    ORF Viral Vector pGMAP000455 Human TIMP1 Adenovirus plasmid
    ORF Viral Vector pGMAP000469 Human TIMP1 Adenovirus plasmid
    ORF Viral Vector pGMAP000553 Human TIMP1 Adenovirus plasmid
    ORF Viral Vector pGMPC001587 Human TIMP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001347 Human TIMP1 Lentivirus particle
    ORF Viral Vector vGMLV000257 Human TIMP1 Lentivirus particle
    ORF Viral Vector vGMAP000455 Human TIMP1 Adenovirus particle
    ORF Viral Vector vGMAP000469 Human TIMP1 Adenovirus particle
    ORF Viral Vector vGMAP000553 Human TIMP1 Adenovirus particle


    Target information

    Target ID GM-SE0506
    Target Name TIMP1
    Gene ID 7076, 21857, 574348, 116510, 101095886, 403816, 282092, 100034220
    Gene Symbol and Synonyms CLGI,EPA,EPO,HCI,TIMP,TIMP-1,TIMP1,TPA-S1
    Uniprot Accession P01033
    Uniprot Entry Name TIMP1_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Diagnostics Biomarker
    Disease Dent disease, Vesicoureteral reflux
    Gene Ensembl ENSG00000102265
    Target Classification Not Available

    This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]



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