Human TGFB3/ARVD/ARVD1 ORF/cDNA clone-Adenovirus plasmid (NM_003239)

SKU: pGMAP-SPh-179
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TGFB3/ARVD/ARVD1 adenoviral expression plasmid for TGFB3 adenovirus packaging, TGFB3 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

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Product Description

Catalog ID pGMAP-SPh-179
Gene Name TGFB3
Accession Number NM_003239
Gene ID 7043
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 1239 bp
Gene Alias ARVD,ARVD1,LDS5,RNHF,TGF-beta3
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter cmv
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T22978-Ab Anti-TGFB3/ ARVD/ ARVD1 monoclonal antibody
    Target Antigen GM-Tg-g-T22978-Ag TGFB3 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T22978 transforming growth factor, beta 3 (TGFB3) protein & antibody
    ORF Viral Vector pGMLP003661 Human TGFB3 Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-039 Human TGFB3 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-179 Human TGFB3 Adenovirus plasmid
    ORF Viral Vector vGMLP003661 Human TGFB3 Lentivirus particle
    ORF Viral Vector vGMLP-SPh-039 Human TGFB3 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-179 Human TGFB3 Adenovirus particle


    Target information

    Target ID GM-T22978
    Target Name TGFB3
    Gene ID 7043, 21809, 703239, 25717, 101098469, 490796, 538957, 100051765
    Gene Symbol and Synonyms ARVD,ARVD1,LDS5,RNHF,TGF-B3,TGF-beta-3,TGF-beta3,Tgfb-3,TGFB3,TGFbeta3
    Uniprot Accession P10600
    Uniprot Entry Name TGFB3_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, Cytokine Target
    Disease Breast Cancer
    Gene Ensembl ENSG00000119699
    Target Classification Checkpoint-Immuno Oncology

    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.