YAP1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of YAP1. The page also collects GeneMedi's different modalities and formats products for YAP1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the YAP1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Target ID | GM-T94048 |
Target Name | YAP1 |
Gene ID | 10413,22601,363014,704382,479465,101101408,100336629,100068834 |
Gene Symbol and Synonyms | COB1,YAP,YAP-1,YAP-65,YAP1,YAP2,YAP65,YKI,Yorkie |
Uniprot Accession | P46937,Q2EJA0 |
Uniprot Entry Name | YAP1_HUMAN,YAP1_RAT |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000137693 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-YAP1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-YAP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-YAP1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-YAP1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species YAP1/ COB1/ YAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
YAP1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made YAP1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMAAV000314 | human YAP1 AAV particle | NM_001130145 | Human | AAV particle | Detail |
vGMAD000620 | human YAP1 Adenovirus particle | NM_001130145.2 | Human | Adenovirus particle | Detail |
pGMLV000567 | human YAP1 Lentivirus plasmid | NM_001130145.2 | Human | Lentivirus plasmid | Detail |
vGMLV000567 | human YAP1 Lentivirus particle | NM_001130145.2 | Human | Lentivirus particle | Detail |
vGMAD000063 | human YAP1 Adenovirus particle | NM_001130145.2 | Human | Adenovirus particle | Detail |
pGMLV000392 | human YAP1 Lentivirus plasmid | NM_001130145 | Human | Lentivirus plasmid | Detail |
vGMLV000392 | human YAP1 Lentivirus particle | NM_001130145 | Human | Lentivirus particle | Detail |
pGMAD000063 | human YAP1 Adenovirus plasmid | NM_001130145.2 | Human | Adenovirus plasmid | Detail |
pGMAAV000314 | human YAP1 AAV plasmid | NM_001130145 | Human | AAV plasmid | Detail |
pGMLV000777 | human YAP1 Lentivirus plasmid | NM_001130145.3 | Human | Lentivirus plasmid | Detail |
pGMAD000620 | human YAP1 Adenovirus plasmid | NM_001130145.2 | Human | Adenovirus plasmid | Detail |
vGMLV000777 | human YAP1 Lentivirus particle | NM_001130145.3 | Human | Lentivirus particle | Detail |
pGMAD000081 | mouse Yap1 Adenovirus plasmid | NM_001171147 | Mouse | Adenovirus plasmid | Detail |
pGMAD000508 | house mouse Yap1 Adenovirus plasmid | NM_001171147.1 | House Mouse | Adenovirus plasmid | Detail |
pGMAAV000106 | mouse Yap1 AAV plasmid | NM_001171147.1 | Mouse | AAV plasmid | Detail |
vGMAD000081 | mouse Yap1 Adenovirus particle | NM_001171147 | Mouse | Adenovirus particle | Detail |
vGMAD000508 | house mouse Yap1 Adenovirus particle | NM_001171147.1 | House Mouse | Adenovirus particle | Detail |
vGMAAV000106 | mouse Yap1 AAV particle | NM_001171147.1 | Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.