Human YAP1/COB1/YAP ORF/cDNA clone-Adenovirus particle (NM_001130145.2)
Cat. No.: vGMAD000063
Pre-made Human YAP1/COB1/YAP Adenovirus for YAP1 overexpression in-vitro and in-vivo. The YAP1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified YAP1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
vGMAD000063 | Human YAP1 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
5E+10PFU (1E+10pfu/ml×5ml) | |||
1E+11PFU (1E+10pfu/ml×10ml) | |||
Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAD000063 |
Gene Name | YAP1 |
Accession Number | NM_001130145.2 |
Gene ID | 10413 |
Species | Human |
Product Type | Adenovirus particle (overexpression) |
Insert Length | 1515 bp |
Gene Alias | COB1,YAP,YAP2,YAP65,YKI |
Fluorescent Reporter | GFP |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | EF1 |
Resistance | Amplicin |
Reference
Data / case study
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Associated products
Target information
Target ID | GM-T94048 |
Target Name | YAP1 |
Gene ID | 10413, 22601, 704382, 363014, 101101408, 479465, 100336629, 100068834 |
Gene Symbol and Synonyms | COB1,YAP,YAP-1,YAP-65,YAP1,YAP2,YAP65,YKI,Yorkie |
Uniprot Accession | P46937 |
Uniprot Entry Name | YAP1_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000137693 |
Target Classification | Tumor-associated antigen (TAA) |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.