GAP43: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of GAP43. The page also collects GeneMedi's different modalities and formats products for GAP43 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GAP43 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Target ID | GM-T93966 |
Target Name | GAP43 |
Gene ID | 2596,14432,29423,711260,478572,493873,281777,100061125 |
Gene Symbol and Synonyms | B-50,Basp2,GAP-43,GAP43,PP46 |
Uniprot Accession | P17677,P07936,Q6S9D9,P06836 |
Uniprot Entry Name | NEUM_HUMAN,NEUM_RAT,NEUM_FELCA,NEUM_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000172020 |
Target Classification | N/A |
Pre-made anti-GAP43 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-GAP43 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GAP43 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-GAP43 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Multi-species NEUM/ GAP43/ B-50 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GAP43 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
GAP43 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made GAP43 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLV000306 | human GAP43 Lentivirus plasmid | NM_002045.3 | Human | Lentivirus plasmid | Detail |
vGMLV000306 | human GAP43 Lentivirus particle | NM_002045.3 | Human | Lentivirus particle | Detail |
pGMLP004662 | human GAP43 Lentivirus plasmid | NM_002045 | Human | Lentivirus plasmid | Detail |
vGMLP004662 | human GAP43 Lentivirus particle | NM_002045 | Human | Lentivirus particle | Detail |
pGMAD000524 | house mouse Gap43 Adenovirus plasmid | NM_008083 | House Mouse | Adenovirus plasmid | Detail |
pGMLPm001202 | mouse Gap43 Lentivirus plasmid | NM_008083 | Mouse | Lentivirus plasmid | Detail |
vGMAD000524 | house mouse Gap43 Adenovirus particle | NM_008083 | House Mouse | Adenovirus particle | Detail |
vGMLPm001202 | mouse Gap43 Lentivirus particle | NM_008083 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.