PRMT5: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of PRMT5. The page also collects GeneMedi's different modalities and formats products for PRMT5 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PRMT5 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Target ID | GM-T82665 |
Target Name | PRMT5 |
Gene ID | 10419,27374,364382,712718,480242,101091118,515594,100052729 |
Gene Symbol and Synonyms | HRMT1L5,HSL7,IBP72,JBP1,PRMT5,SKB1,SKB1Hs |
Uniprot Accession | O14744,A7YW45 |
Uniprot Entry Name | ANM5_HUMAN,ANM5_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Prostate Cancer |
Gene Ensembl | ENSG00000100462 |
Target Classification | N/A |
Pre-made anti-PRMT5 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-PRMT5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PRMT5 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-PRMT5 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species ANM5/ PRMT5/ HRMT1L5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRMT5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
PRMT5 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made PRMT5 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLV000196 | human PRMT5 Lentivirus particle | NM_006109 | Human | Lentivirus particle | Detail |
vGMAD000192 | human PRMT5 Adenovirus particle | NM_006109.4 | Human | Adenovirus particle | Detail |
vGMLV000778 | human PRMT5 Lentivirus particle | NM_006109.5 | Human | Lentivirus particle | Detail |
pGMLV000778 | human PRMT5 Lentivirus plasmid | NM_006109.5 | Human | Lentivirus plasmid | Detail |
pGMAD000192 | human PRMT5 Adenovirus plasmid | NM_006109.4 | Human | Adenovirus plasmid | Detail |
pGMLV000196 | human PRMT5 Lentivirus plasmid | NM_006109 | Human | Lentivirus plasmid | Detail |
pGMLPm003039 | mouse Prmt5 Lentivirus plasmid | NM_013768 | Mouse | Lentivirus plasmid | Detail |
vGMLPm003039 | mouse Prmt5 Lentivirus particle | NM_013768 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.