GATA4: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of GATA4. The page also collects GeneMedi's different modalities and formats products for GATA4 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GATA4 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Target ID | GM-T51817 |
Target Name | GATA4 |
Gene ID | 2626,14463,54254,696775,486079,101086140,327716,100065126 |
Gene Symbol and Synonyms | ASD2,Gata-4,GATA4,TACHD,TOF,VSD1 |
Uniprot Accession | P43694,P46152,Q0Q0E4 |
Uniprot Entry Name | GATA4_HUMAN,GATA4_RAT,GATA4_CANLF |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Head and Neck Cancer |
Gene Ensembl | ENSG00000136574 |
Target Classification | N/A |
Pre-made anti-GATA4 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-GATA4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GATA4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-GATA4 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species GATA4/ ASD2/ TACHD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GATA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
GATA4 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made GATA4 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMAD000115 | human GATA4 Adenovirus particle | NM_002052.5 | Human | Adenovirus particle | Detail |
pGMAD000115 | human GATA4 Adenovirus plasmid | NM_002052.5 | Human | Adenovirus plasmid | Detail |
pGMLV000028 | rat Gata4 Lentivirus plasmid | NM_144730 | Rat | Lentivirus plasmid | Detail |
pGMAAV000160 | rat Gata4 AAV plasmid | NM_144730.1 | Rat | AAV plasmid | Detail |
pGMAAV000209 | house mouse Gata4 AAV plasmid | NM_001310610 | House Mouse | AAV plasmid | Detail |
pGMAAV000268 | house mouse Gata4 AAV plasmid | NM_001310610 | House Mouse | AAV plasmid | Detail |
pGMLPm004341 | mouse Gata4 Lentivirus plasmid | NM_001310610 | Mouse | Lentivirus plasmid | Detail |
vGMLV000028 | rat Gata4 Lentivirus particle | NM_144730 | Rat | Lentivirus particle | Detail |
vGMAAV000160 | rat Gata4 AAV particle | NM_144730.1 | Rat | AAV particle | Detail |
vGMAAV000209 | house mouse Gata4 AAV particle | NM_001310610 | House Mouse | AAV particle | Detail |
vGMAAV000268 | house mouse Gata4 AAV particle | NM_001310610 | House Mouse | AAV particle | Detail |
vGMLPm004341 | mouse Gata4 Lentivirus particle | NM_001310610 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.