LPAR2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of LPAR2. The page also collects GeneMedi's different modalities and formats products for LPAR2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the LPAR2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Target ID | GM-T39380 |
Target Name | LPAR2 |
Gene ID | 9170,53978,498609,719844,484802,101100950,509748,102147510 |
Gene Symbol and Synonyms | EDG-4,EDG4,IPA2,LPA-2,LPA2,LPAR2,PBX4,RGD1561336 |
Uniprot Accession | Q9HBW0 |
Uniprot Entry Name | LPAR2_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000064547 |
Target Classification | GPCR |
Pre-made anti-LPAR2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-LPAR2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-LPAR2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-LPAR2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Multi-species LPAR2/ EDG-4/ EDG4 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LPAR2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
LPAR2 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made LPAR2 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP003145 | human LPAR2 Lentivirus particle | NM_004720 | Human | Lentivirus particle | Detail |
pGMLP003145 | human LPAR2 Lentivirus plasmid | NM_004720 | Human | Lentivirus plasmid | Detail |
vGMLV000233 | human LPAR2 Lentivirus particle | NM_004720.5 | Human | Lentivirus particle | Detail |
pGMLV000233 | human LPAR2 Lentivirus plasmid | NM_004720.5 | Human | Lentivirus plasmid | Detail |
pGMAD000569 | house mouse Lpar2 Adenovirus plasmid | NM_020028.3 | House Mouse | Adenovirus plasmid | Detail |
pGMLPm001715 | mouse Lpar2 Lentivirus plasmid | NM_020028.3 | Mouse | Lentivirus plasmid | Detail |
vGMAD000569 | house mouse Lpar2 Adenovirus particle | NM_020028.3 | House Mouse | Adenovirus particle | Detail |
vGMLPm001715 | mouse Lpar2 Lentivirus particle | NM_020028.3 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.