CGA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of CGA. The page also collects GeneMedi's different modalities and formats products for CGA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CGA target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Target IDGM-T16650
Target NameCGA
Gene ID1081,12640,116700,697859,403483,751819,280749,100034174
Gene Symbol and SynonymsaGSU,alpha-GSU,alphaGSU,alphaSU,CG,CG-ALPHA,CGA,FSH-alpha,FSHA,GPA1,GPHa,GPHA1,GPHalpha,HCG,LHA,LSH-alpha,TSH-alpha,TSHA
Uniprot AccessionP01215,P11962,P22762,Q9XSW8,Q52R91,P01217,P01220
Uniprot Entry NameGLHA_HUMAN,GLHA_MACMU,GLHA_RAT,GLHA_FELCA,GLHA_CANLF,GLHA_BOVIN,GLHA_HORSE
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target
DiseaseDrug Abuse
Gene EnsemblENSG00000135346
Target ClassificationN/A


Pre-made anti-CGA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-CGA benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CGA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-CGA monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Recombinant multi-species GLHA/ CGA/ CG-ALPHA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
CGA proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made CGA viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMAP000267Human CGA Adenovirus plasmidBC020782HumanAdenovirus plasmidDetail
vGMAP000267Human CGA Adenovirus particleBC020782HumanAdenovirus particleDetail
pGMLV000787house mouse Cga Lentivirus plasmidNM_009889.2House MouseLentivirus plasmidDetail
pGMAAV000302house mouse Cga AAV plasmidNM_009889.2House MouseAAV plasmidDetail
pGMLPm004316mouse Cga Lentivirus plasmidNM_009889MouseLentivirus plasmidDetail
vGMLV000787house mouse Cga Lentivirus particleNM_009889.2House MouseLentivirus particleDetail
vGMAAV000302house mouse Cga AAV particleNM_009889.2House MouseAAV particleDetail
vGMLPm004316mouse Cga Lentivirus particleNM_009889MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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