CGA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CGA. The page also collects GeneMedi's different modalities and formats products for CGA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CGA target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Target ID | GM-T16650 |
Target Name | CGA |
Gene ID | 1081,12640,116700,697859,403483,751819,280749,100034174 |
Gene Symbol and Synonyms | aGSU,alpha-GSU,alphaGSU,alphaSU,CG,CG-ALPHA,CGA,FSH-alpha,FSHA,GPA1,GPHa,GPHA1,GPHalpha,HCG,LHA,LSH-alpha,TSH-alpha,TSHA |
Uniprot Accession | P01215,P11962,P22762,Q9XSW8,Q52R91,P01217,P01220 |
Uniprot Entry Name | GLHA_HUMAN,GLHA_MACMU,GLHA_RAT,GLHA_FELCA,GLHA_CANLF,GLHA_BOVIN,GLHA_HORSE |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Drug Abuse |
Gene Ensembl | ENSG00000135346 |
Target Classification | N/A |
Pre-made anti-CGA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CGA benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CGA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-CGA monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Recombinant multi-species GLHA/ CGA/ CG-ALPHA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
CGA protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made CGA viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMAP000267 | Human CGA Adenovirus plasmid | BC020782 | Human | Adenovirus plasmid | Detail |
vGMAP000267 | Human CGA Adenovirus particle | BC020782 | Human | Adenovirus particle | Detail |
pGMLV000787 | house mouse Cga Lentivirus plasmid | NM_009889.2 | House Mouse | Lentivirus plasmid | Detail |
pGMAAV000302 | house mouse Cga AAV plasmid | NM_009889.2 | House Mouse | AAV plasmid | Detail |
pGMLPm004316 | mouse Cga Lentivirus plasmid | NM_009889 | Mouse | Lentivirus plasmid | Detail |
vGMLV000787 | house mouse Cga Lentivirus particle | NM_009889.2 | House Mouse | Lentivirus particle | Detail |
vGMAAV000302 | house mouse Cga AAV particle | NM_009889.2 | House Mouse | AAV particle | Detail |
vGMLPm004316 | mouse Cga Lentivirus particle | NM_009889 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.