IFNA1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of IFNA1. The page also collects GeneMedi's different modalities and formats products for IFNA1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the IFNA1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia. [provided by RefSeq, Aug 2020]
Target ID | GM-SE0626 |
Target Name | IFNA1 |
Gene ID | 3439 |
Gene Symbol and Synonyms | IFL,IFN,IFN-ALPHA,IFN-alphaD,IFNA1,IFNA13,IFNA@,leIF D |
Uniprot Accession | N/A |
Uniprot Entry Name | |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, INN Index, Cytokine Target |
Disease | leukemia |
Gene Ensembl | ENSG00000197919 |
Target Classification | N/A |
Pre-made IFNA1-specific INN-index biosimilar (antibody&conjugates)
Anti-IFNA1 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Cat No. | Products Name (INN Index) | INN Name | Previous Name | Target | Format | Detail |
GMP-Bios-INN-849 | Pre-Made Faralimomab Biosimilar, Whole Mab, Anti-Ifna1 Antibody: Anti-IFL/IFN/IFN-ALPHA/IFN-alphaD/IFNA13/leIF D therapeutic antibody | faralimomab | IFNA1 | Whole? mAb | Detail | |
GMP-Bios-INN-760 | Pre-Made Bifarcept Biosimilar, Recombinant Protein targeting IFNA1: Recombinant therapeutic protein targeting IFL/IFN/IFN-ALPHA/IFN-alphaD/IFNA13/leIF D | bifarcept | IFNA1 | Recombinant Protein | Detail | |
GMP-Bios-ab-494 | Pre-Made Rontalizumab biosimilar, Whole mAb, Anti-IFNA1 Antibody: Anti-IFL/IFN3/leIF DD therapeutic antibody | Rontalizumab | IFNA1 | Whole mAb | Detail | |
GMP-Bios-ab-519 | Pre-Made Sifalimumab biosimilar, Whole mAb, Anti-IFNA1 Antibody: Anti-IFL/IFN3/leIF DD therapeutic antibody | Sifalimumab | IFNA1 | Whole mAb | Detail |
Click to check more INN-indexed antibody & protein biosimilar
Pre-made anti-IFNA1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-IFNA1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IFNA1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-IFNA1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
Recombinant multi-species IFNA1/ IFL/ IFN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFNA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
IFNA1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Cytokine Products for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interferon, alpha 1 (IFNA1) His+Avi (Biotinylated) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene.? Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon (IFN-gamma; MIM 147570) is produced by mitogen- or antigen-stimulated T lymphocytes.[supplied by OMIM]
Target | Species | Antigen Product Name | Bioactivity validation of Antigen | Antibody Product Name | Bioactivity validation of Antibodies | Detail |
IFNA1 | Human, Cynomolgus/Rhesus macaque, rat, mouse | interferon, alpha 1 (IFNA1) protein | Affintiy&bioactivity validated by ELISA, cell culture validated | Anti-IFNA1 monoclonal antibody | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). | Detail |
Click to check more Cytokine Products
Pre-made IFNA1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMAP000481 | Human IFNA1 Adenovirus particle | BC112300 | Human | Adenovirus particle | Detail |
vGMAD000576 | human IFNA1 Adenovirus particle | NM_024013.2 | Human | Adenovirus particle | Detail |
pGMAP000481 | Human IFNA1 Adenovirus plasmid | BC112300 | Human | Adenovirus plasmid | Detail |
pGMLP000551 | human IFNA1 Lentivirus plasmid | NM_024013 | Human | Lentivirus plasmid | Detail |
vGMLP000551 | human IFNA1 Lentivirus particle | NM_024013 | Human | Lentivirus particle | Detail |
pGMAD000576 | human IFNA1 Adenovirus plasmid | NM_024013.2 | Human | Adenovirus plasmid | Detail |
pGMLPm000108 | mouse Ifna1 Lentivirus plasmid | NM_010502 | Mouse | Lentivirus plasmid | Detail |
vGMLPm000108 | mouse Ifna1 Lentivirus particle | NM_010502 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.