IFNA1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of IFNA1. The page also collects GeneMedi's different modalities and formats products for IFNA1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the IFNA1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia. [provided by RefSeq, Aug 2020]

Target IDGM-SE0626
Target NameIFNA1
Gene ID3439
Gene Symbol and SynonymsIFL,IFN,IFN-ALPHA,IFN-alphaD,IFNA1,IFNA13,IFNA@,leIF D
Uniprot AccessionN/A
Uniprot Entry Name
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target, INN Index, Cytokine Target
Diseaseleukemia
Gene EnsemblENSG00000197919
Target ClassificationN/A


Pre-made IFNA1-specific INN-index biosimilar (antibody&conjugates)

Anti-IFNA1 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Cat No.Products Name (INN Index)INN Name Previous Name Target FormatDetail
GMP-Bios-INN-849Pre-Made Faralimomab Biosimilar, Whole Mab, Anti-Ifna1 Antibody: Anti-IFL/IFN/IFN-ALPHA/IFN-alphaD/IFNA13/leIF D therapeutic antibodyfaralimomabIFNA1Whole? mAbDetail
GMP-Bios-INN-760Pre-Made Bifarcept Biosimilar, Recombinant Protein targeting IFNA1: Recombinant therapeutic protein targeting IFL/IFN/IFN-ALPHA/IFN-alphaD/IFNA13/leIF DbifarceptIFNA1Recombinant ProteinDetail
GMP-Bios-ab-494Pre-Made Rontalizumab biosimilar, Whole mAb, Anti-IFNA1 Antibody: Anti-IFL/IFN3/leIF DD therapeutic antibodyRontalizumabIFNA1Whole mAbDetail
GMP-Bios-ab-519Pre-Made Sifalimumab biosimilar, Whole mAb, Anti-IFNA1 Antibody: Anti-IFL/IFN3/leIF DD therapeutic antibodySifalimumabIFNA1Whole mAbDetail

Click to check more INN-indexed antibody & protein biosimilar



Pre-made anti-IFNA1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-IFNA1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IFNA1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-IFNA1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail



Recombinant multi-species IFNA1/ IFL/ IFN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFNA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
IFNA1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Cytokine Products for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interferon, alpha 1 (IFNA1) His+Avi (Biotinylated) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene.? Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon (IFN-gamma; MIM 147570) is produced by mitogen- or antigen-stimulated T lymphocytes.[supplied by OMIM]

TargetSpeciesAntigen Product NameBioactivity validation of AntigenAntibody Product NameBioactivity validation of AntibodiesDetail
IFNA1Human, Cynomolgus/Rhesus macaque, rat, mouseinterferon, alpha 1 (IFNA1) proteinAffintiy&bioactivity validated by ELISA, cell culture validatedAnti-IFNA1 monoclonal antibodyBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).Detail

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Pre-made IFNA1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMAP000481Human IFNA1 Adenovirus particleBC112300HumanAdenovirus particleDetail
vGMAD000576human IFNA1 Adenovirus particleNM_024013.2HumanAdenovirus particleDetail
pGMAP000481Human IFNA1 Adenovirus plasmidBC112300HumanAdenovirus plasmidDetail
pGMLP000551human IFNA1 Lentivirus plasmidNM_024013HumanLentivirus plasmidDetail
vGMLP000551human IFNA1 Lentivirus particleNM_024013HumanLentivirus particleDetail
pGMAD000576human IFNA1 Adenovirus plasmidNM_024013.2HumanAdenovirus plasmidDetail
pGMLPm000108mouse Ifna1 Lentivirus plasmidNM_010502MouseLentivirus plasmidDetail
vGMLPm000108mouse Ifna1 Lentivirus particleNM_010502MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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