HPX: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HPX. The page also collects GeneMedi's different modalities and formats products for HPX in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HPX target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]
Target ID | GM-SE0265 |
Target Name | HPX |
Gene ID | 3263,15458,58917,711007,610982,101091144,534509,100055123 |
Gene Symbol and Synonyms | HPX,Hpxn,HX |
Uniprot Accession | P02790,P20059,Q3SZV7 |
Uniprot Entry Name | HEMO_HUMAN,HEMO_RAT,HEMO_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | Lung cancer, Malignant neoplasm of bladder, Nephrotic syndrome with focal and segmental glomerular lesions, Dent disease, Diabetic Nephropathy |
Gene Ensembl | ENSG00000110169 |
Target Classification | N/A |
Pre-made anti-HPX inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HPX benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HPX mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-HPX monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Recombinant multi-species HEMO/ HPX/ HX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
HPX protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HPX viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP003727 | human HPX Lentivirus particle | NM_000613 | Human | Lentivirus particle | Detail |
pGMLP003727 | human HPX Lentivirus plasmid | NM_000613 | Human | Lentivirus plasmid | Detail |
pGMLPm001838 | mouse Hpx Lentivirus plasmid | NM_017371 | Mouse | Lentivirus plasmid | Detail |
vGMLPm001838 | mouse Hpx Lentivirus particle | NM_017371 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.