VDUP1/TXNIP: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of VDUP1/TXNIP. The page also collects GeneMedi's different modalities and formats products for VDUP1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the VDUP1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Target ID | GM-IP0163 |
Target Name | VDUP1 |
Gene ID | 10628,56338,117514,698683,475829,101099739,506790,111773538 |
Gene Symbol and Synonyms | 1200008J08Rik,ARRDC6,EST01027,HHCPA78,Hyplip1,Tbp-2,THIF,TXNIP,VDUP1 |
Uniprot Accession | Q9H3M7,Q5M7W1 |
Uniprot Entry Name | TXNIP_HUMAN,TXNIP_RAT |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000265972 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-VDUP1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-VDUP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-VDUP1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-VDUP1/TXNIP monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species TXNIP/ VDUP1/ ARRDC6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VDUP1/TXNIP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
VDUP1/TXNIP protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made TXNIP viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLV000188 | human TXNIP Lentivirus plasmid | NM_006472.5 | Human | Lentivirus plasmid | Detail |
pGMAP000591 | human TXNIP Adenovirus plasmid | NM_006472.5 | Human | Adenovirus plasmid | Detail |
vGMAP000591 | human TXNIP Adenovirus particle | NM_006472.5 | Human | Adenovirus particle | Detail |
vGMLV000188 | human TXNIP Lentivirus particle | NM_006472.5 | Human | Lentivirus particle | Detail |
pGMAD000027 | mouse Txnip Adenovirus plasmid | NM_001009935.2 | Mouse | Adenovirus plasmid | Detail |
pGMAAV000006 | mouse Txnip AAV plasmid | NM_001009935.2 | Mouse | AAV plasmid | Detail |
vGMAD000027 | mouse Txnip Adenovirus particle | NM_001009935.2 | Mouse | Adenovirus particle | Detail |
vGMAAV000006 | mouse Txnip AAV particle | NM_001009935.2 | Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.