VDAC2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of VDAC2. The page also collects GeneMedi's different modalities and formats products for VDAC2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the VDAC2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Target ID | GM-IP0121 |
Target Name | VDAC2 |
Gene ID | 7417,22334,83531,704257,479255,101092793,282120,100064276 |
Gene Symbol and Synonyms | mVDAC2,mVDAC6,POR,VDAC2,Vdac6 |
Uniprot Accession | P45880,P81155,P68002 |
Uniprot Entry Name | VDAC2_HUMAN,VDAC2_RAT,VDAC2_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000165637 |
Target Classification | N/A |
Pre-made anti-VDAC2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-VDAC2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-VDAC2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-VDAC2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species VDAC2/ POR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VDAC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
VDAC2 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made VDAC2 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLV000368 | human VDAC2 Lentivirus plasmid | NM_001184783.1 | Human | Lentivirus plasmid | Detail |
vGMLP002688 | human VDAC2 Lentivirus particle | NM_001184783 | Human | Lentivirus particle | Detail |
vGMLV000368 | human VDAC2 Lentivirus particle | NM_001184783.1 | Human | Lentivirus particle | Detail |
pGMAP000584 | Human VDAC2 Adenovirus plasmid | NM_001184783.1 | Human | Adenovirus plasmid | Detail |
pGMLP002688 | human VDAC2 Lentivirus plasmid | NM_001184783 | Human | Lentivirus plasmid | Detail |
vGMAP000584 | Human VDAC2 Adenovirus particle | NM_001184783.1 | Human | Adenovirus particle | Detail |
pGMLPm004711 | mouse Vdac2 Lentivirus plasmid | NM_011695 | Mouse | Lentivirus plasmid | Detail |
vGMLPm004711 | mouse Vdac2 Lentivirus particle | NM_011695 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.