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Anti-VDAC2 monoclonal antibody
Pre-made anti-VDAC2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to VDAC2/VDAC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0121-Ab-1/ GM-Tg-hg-IP0121-Ab-2 | Anti-Human VDAC2 monoclonal antibody | Human |
| GM-Tg-rg-IP0121-Ab-1/ GM-Tg-rg-IP0121-Ab-2 | Anti-Rat VDAC2 monoclonal antibody | Rat |
| GM-Tg-mg-IP0121-Ab-1/ GM-Tg-mg-IP0121-Ab-2 | Anti-Mouse VDAC2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0121-Ab-1/ GM-Tg-cynog-IP0121-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VDAC2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0121-Ab-1/ GM-Tg-felg-IP0121-Ab-2 | Anti-Feline VDAC2 monoclonal antibody | Feline |
| GM-Tg-cang-IP0121-Ab-1/ GM-Tg-cang-IP0121-Ab-2 | Anti-Canine VDAC2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0121-Ab-1/ GM-Tg-bovg-IP0121-Ab-2 | Anti-Bovine VDAC2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0121-Ab-1/ GM-Tg-equg-IP0121-Ab-2 | Anti-Equine VDAC2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0121-Ab-1/ GM-Tg-hg-IP0121-Ab-2; GM-Tg-rg-IP0121-Ab-1/ GM-Tg-rg-IP0121-Ab-2; GM-Tg-mg-IP0121-Ab-1/ GM-Tg-mg-IP0121-Ab-2; GM-Tg-cynog-IP0121-Ab-1/ GM-Tg-cynog-IP0121-Ab-2; GM-Tg-felg-IP0121-Ab-1/ GM-Tg-felg-IP0121-Ab-2; GM-Tg-cang-IP0121-Ab-1/ GM-Tg-cang-IP0121-Ab-2; GM-Tg-bovg-IP0121-Ab-1/ GM-Tg-bovg-IP0121-Ab-2; GM-Tg-equg-IP0121-Ab-1/ GM-Tg-equg-IP0121-Ab-2 |
| Products Name | Anti-VDAC2 monoclonal antibody |
| Format | mab |
| Target Name | VDAC2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-VDAC2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0121-Ag-1 | Recombinant multi-species VDAC2/ POR protein |
| ORF Viral Vector | pGMLV000368 | human VDAC2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002688 | human VDAC2 Lentivirus particle |
| ORF Viral Vector | vGMLV000368 | human VDAC2 Lentivirus particle |
| ORF Viral Vector | pGMAP000584 | Human VDAC2 Adenovirus plasmid |
| ORF Viral Vector | pGMLP002688 | human VDAC2 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000584 | Human VDAC2 Adenovirus particle |
| ORF Viral Vector | pGMLPm004711 | mouse Vdac2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004711 | mouse Vdac2 Lentivirus particle |
Target information
| Target ID | GM-IP0121 |
| Target Name | VDAC2 |
| Gene ID | 7417,22334,83531,704257,479255,101092793,282120,100064276 |
| Gene Symbol and Synonyms | mVDAC2,mVDAC6,POR,VDAC2,Vdac6 |
| Uniprot Accession | P45880,P81155,P68002 |
| Uniprot Entry Name | VDAC2_HUMAN,VDAC2_RAT,VDAC2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000165637 |
| Target Classification | N/A |
The target: VDAC2, gene name: VDAC2, also named as POR. This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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