Diphtheria toxin, A-subunit antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Diphtheria toxin, A-subunit antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-164-11. BSA-Diphtheria toxin, A-subunit
2. Anti-Diphtheria toxin, A-subunit mouse monoclonal antibody
$2709.00
GMP-SMT-164-21. OVA-Diphtheria toxin, A-subunit
2. Anti-Diphtheria toxin, A-subunit mouse monoclonal antibody
$2709.00
GMP-SMT-164-31. BSA-Diphtheria toxin, A-subunit
2. Anti-Diphtheria toxin, A-subunit human monoclonal antibody
$2709.00
GMP-SMT-164-41. OVA-Diphtheria toxin, A-subunit
2. Anti-Diphtheria toxin, A-subunit human monoclonal antibody
$2709.00
GMP-SMT-164-Ag-1BSA-Diphtheria toxin, A-subunit$756.00
GMP-SMT-164-Ag-2OVA-Diphtheria toxin, A-subunit$756.00
GMP-SMT-164-Ab-1Anti-Diphtheria toxin, A-subunit mouse monoclonal antibody$1953.00
GMP-SMT-164-Ab-2Anti-Diphtheria toxin, A-subunit human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Diphtheria toxin, A-subunit

Cat No.GMP-SMT-164-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Diphtheria toxin, A-subunit with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Diphtheria toxin, A-subunit had been validated with our anti-Hapten antibody Anti-Diphtheria toxin, A-subunit mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Diphtheria toxin, A-subunit

Cat No.GMP-SMT-164-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Diphtheria toxin, A-subunit with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Diphtheria toxin, A-subunit had been validated with our anti-Hapten antibody Anti-Diphtheria toxin, A-subunit mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Diphtheria toxin, A-subunit mouse monoclonal antibody

Cat No.GMP-SMT-164-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.9-1
Products descriptionThe anti-Hapten antibody against hapten Diphtheria toxin, A-subunit had been validated with our hapten hapten-carrier conjugates BSA-Diphtheria toxin, A-subunit via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Diphtheria toxin, A-subunit human monoclonal antibody

Cat No.GMP-SMT-164-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.9-1
Products descriptionThe anti-Hapten antibody against hapten Diphtheria toxin, A-subunit had been validated with our hapten hapten-carrier conjugates BSA-Diphtheria toxin, A-subunit via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Biomarker Information


    1. Diphtheria Toxin, A-subunit:

    Diphtheria toxin, A-subunit, represents a pivotal protein component originating from the potent diphtheria toxin, a virulence factor produced by the bacterium Corynebacterium diphtheriae. It is noteworthy to emphasize that, unlike mycotoxins, which are toxic compounds stemming from molds and fungi, Diphtheria toxin, A-subunit, belongs to the class of bacterial toxins and does not share direct involvement in mycotoxin-related processes. Its prominence lies in its indispensable role within the pathogenesis of diphtheria, a bacterial disease characterized by severe respiratory symptoms and the adverse tissue effects induced by the toxin's action.

    Role in Mycotoxins:

    It is imperative to underscore that Diphtheria toxin, A-subunit, does not partake in mycotoxin-related processes. Instead, its significance is deeply rooted in the realm of diphtheria diagnosis, research, and public health interventions. Mycotoxins and bacterial toxins are distinctive entities, each governed by its unique mechanisms of action, physiological targets, and implications.

    2. Why Measure Diphtheria Toxin, A-subunit?

    The rationale for measuring Diphtheria toxin, A-subunit, is multifaceted and central to the realms of diphtheria diagnosis, scientific inquiry, and public health endeavors. Here are the salient reasons substantiating the necessity of measuring Diphtheria toxin, A-subunit:

    a. Diphtheria Diagnosis: The detection and quantification of Diphtheria toxin, A-subunit, within clinical samples stand as fundamental diagnostic markers for confirming diphtheria infections. This assessment allows for the expeditious identification of afflicted individuals, enabling timely medical intervention and the administration of appropriate treatment regimens. Such early interventions significantly reduce the severity and morbidity associated with diphtheria.

    b. Vaccine Efficacy Assessment: Measurement of Diphtheria toxin, A-subunit antibodies in the bloodstream constitutes an essential tool for evaluating the effectiveness of diphtheria vaccination. By monitoring the presence and levels of these antibodies, healthcare professionals can ascertain the immunity status of individuals, particularly children who are susceptible to diphtheria. This assessment ensures that vaccination programs deliver and maintain adequate protection against diphtheria.

    c. Epidemiological Surveillance: The quantification of Diphtheria toxin, A-subunit, plays an integral role in epidemiological studies focused on monitoring the prevalence and distribution of diphtheria within specific geographic regions or populations. Such surveillance efforts provide crucial data for public health authorities and policymakers, aiding in the formulation of targeted interventions and vaccination campaigns. This proactive approach contributes significantly to disease control and prevention.

    d. Research Advancements: Scientists and researchers dedicated to unraveling the intricacies of diphtheria and related bacterial toxins rely extensively on precise measurements of Diphtheria toxin, A-subunit. This scientific endeavor seeks to elucidate the underlying mechanisms of action, pathogenesis, and host-pathogen interactions associated with diphtheria toxin. Additionally, these measurements inform the development of potential therapeutic interventions, novel vaccine formulations, and innovative strategies for combating diphtheria.

    In summary, Diphtheria toxin, A-subunit, while unrelated to mycotoxins, assumes a pivotal role in the landscape of diphtheria diagnosis, vaccine efficacy evaluation, epidemiological surveillance, and scientific research. Its measurement represents an indispensable tool in safeguarding public health, enhancing our comprehension of diphtheria and bacterial toxins, and advancing medical and scientific progress in the domain of infectious diseases.



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