Mycotoxins compound antibody & antigen (hapten) for immunoassay and food/feed safety rapid test

Mycotoxins are toxic compounds found in the category of natural contaminants that are produced by molds that can inhabit different food crops especially the cereal grains, nuts and seeds. These toxic substances play a significant role in affecting human and animal health through various ways that include; acute toxic effects, carcinogenic effects, mutagenic effects, and immunosuppressive effects. With more detailed information on particular individual toxins the application for diagnostics and therapeutics has arisen for several of these mycotoxins. Thus, GeneMedi can change diagnostics and therapeutics of mycotoxin individually by introducing its either anti-small molecule antibodies or small molecules competitive antigens. Numerous biologics in this category are characterised for outstanding selectivity and high efficiency when recognising and binding mycotoxins which, therefore, do not cause any adverse effects on a human body.

According to the chemical structure of the toxic compounds as well as the origin, mycotoxins can be grouped as follows. Some of the classes of mycotoxins include; the aflatoxins, trichothecenes, ochratoxins, zearalenone and many more. Each category has a few significant proteins with various roles in the body and uses in medicine. Among the mycotoxins, Aflatoxins produced from Aspergillus species are carcinogenic to humans and animals affecting the liver. For detecting and proving aflatoxins and for the development of therapy of aflatoxin poisoning GeneMedi is offering its products namely: anti-small molecule antibodies and small molecules competitive antigens. Fusarium species synthesize trichothecenes that affect humans and animals through vomiting, diarrhea and they can cause oral lesions. The application of GeneMedi’s product includes identification and measurement of trichothecenes and creation of treatments such as monoclonal antibodies to prevent and cure trichothecene toxicity. Ochratoxins are mycotoxins generated by Aspergillus and penicillium with effects on humans and animals including, damaging impact to the kidney and cancerous effects. Concerning the commercial application of GeneMedi’s product, it can be utilized in ochratoxins detection and quantification, and favorable therapeutic agents such as the application of competitive inhibitors in ochratoxin poisoning prevention and treatment.

Altogether, the strategic product line of GeneMedi’s existing anti-small molecule antibodies and small molecules competitive antigens includes extensive potential in the aspect of mycotoxin diagnostics and treatment. The cofocusing of specific mycotoxins also present health management with opportunities for molecular and targeted treatments. Mycotoxin poisoning can be a huge problem for human health and using GeneMedi’s product one can enhance the diagnostic and therapeutic approaches to this illness and consequently increase the level of patients’ quality of life. The GeneMedi’s product can scan the small molecule of MYCOTOXINS from the different sample by the ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immunoassay (TINIA), immunonephelometry and POCT and these detection methods improve the sensitivity.

Q&A

Q1: What are mycotoxins?
A1: A mycotoxin specifically refers to a toxic substance that is created by fungi that can infest most food crops, and these include grains and nuts, seeds as well.

Q2: What are the possible outcomes of mycotoxins?
A2: A wide variety of toxic effects on human and animal health have been reported through mycotoxins they include; acute toxicity, carcinogenicity, mutagenicity and immunosuppression.

Q3: What is the mode of action of GeneMedi’s products in relation to combating the effects of mycotoxins?
A3: Some of GeneMedi’s anti-small molecule antibodies, and their small molecules competitive antigens products have been produced to detect and eliminate the mycotoxins hence safeguarding man’s health from any adverse impacts from those toxins.

Q4: Could you please state some of the instances of mycotoxins?
A4: Some of the mycotoxins are aflatoxins, trichothecenes, ochratoxins, and zearalenone and they cause several diseases in animals and are carcinogenic to humans. Therefore, they have different uses in therapy concerning their category and primary purpose.

Q5: The following benefits in diagnosing and treating mycotoxin poisoning can be realized if GeneMedi’s products were to be used.
A5: The products offered at GeneMedi have the specificity and effectiveness to identify varying mycotoxins presence and in-turn its quantities which help in giving personalized treatments and medication for mycotoxin poisoning .