Vomitoxin antibody/antigen (BSA/OVA/KLH conjugated hapten)
anti-Vomitoxin antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-SMT-151-1 | 1. BSA-Vomitoxin 2. Anti-Vomitoxin mouse monoclonal antibody | $2709.00 |
GMP-SMT-151-2 | 1. OVA-Vomitoxin 2. Anti-Vomitoxin mouse monoclonal antibody | $2709.00 |
GMP-SMT-151-3 | 1. BSA-Vomitoxin 2. Anti-Vomitoxin human monoclonal antibody | $2709.00 |
GMP-SMT-151-4 | 1. OVA-Vomitoxin 2. Anti-Vomitoxin human monoclonal antibody | $2709.00 |
GMP-SMT-151-Ag-1 | BSA-Vomitoxin | $756.00 |
GMP-SMT-151-Ag-2 | OVA-Vomitoxin | $756.00 |
GMP-SMT-151-Ab-1 | Anti-Vomitoxin mouse monoclonal antibody | $1953.00 |
GMP-SMT-151-Ab-2 | Anti-Vomitoxin human monoclonal antibody | $1953.00 |
Size: 1mg | 10mg | 100mg
Product Description
BSA-Vomitoxin
Cat No. | GMP-SMT-151-Ag-1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates BSA-Vomitoxin with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Vomitoxin had been validated with our anti-Hapten antibody Anti-Vomitoxin mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
OVA-Vomitoxin
Cat No. | GMP-SMT-151-Ag-2 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates OVA-Vomitoxin with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Vomitoxin had been validated with our anti-Hapten antibody Anti-Vomitoxin mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Vomitoxin mouse monoclonal antibody
Cat No. | GMP-SMT-151-Ab-1 |
Host of Antibody | Mouse IgG |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 30.00 |
Products description | The anti-Hapten antibody against hapten Vomitoxin had been validated with our hapten hapten-carrier conjugates BSA-Vomitoxin via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Vomitoxin human monoclonal antibody
Cat No. | GMP-SMT-151-Ab-2 |
Host of Antibody | Human IgG1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 30.00 |
Products description | The anti-Hapten antibody against hapten Vomitoxin had been validated with our hapten hapten-carrier conjugates BSA-Vomitoxin via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Biomarker Information
1. Vomitoxin (Deoxynivalenol) and Its Significance in Mycotoxins:
Vomitoxin, scientifically known as Deoxynivalenol (DON), holds a paramount position within the spectrum of mycotoxins, a class of toxic secondary metabolites produced by various fungi. Its significance lies in its prevalence and the profound implications it has across multiple domains, most notably in the realms of food safety, animal health, and crop quality. Understanding the role of Vomitoxin within the broader context of mycotoxins is pivotal for comprehending the challenges it poses.
Vomitoxin, a mycotoxin belonging to the trichothecene group, is frequently encountered in cereal grains, with wheat, barley, oats, and corn being primary hosts. It is produced by fungi of the Fusarium genus, particularly Fusarium graminearum and Fusarium culmorum. These fungi thrive in various climatic conditions, leading to the widespread contamination of grains. The consequences of Vomitoxin contamination are far-reaching, encompassing not only economic losses but also threats to human and animal health.
In terms of its chemical structure, Vomitoxin is characterized by a tricyclic sesquiterpene core, a hallmark of trichothecenes. Its toxicity arises from its ability to inhibit protein synthesis, which can lead to a range of adverse effects when ingested by humans and animals. The consequences of Vomitoxin exposure include gastrointestinal distress, emesis (vomiting, hence the name "Vomitoxin"), immunosuppression, and reduced growth rates in livestock. Therefore, Vomitoxin plays a pivotal role in the multifaceted landscape of mycotoxins, necessitating rigorous monitoring and mitigation efforts in the agricultural and food sectors.
2. The Imperative of Vomitoxin Measurement:
a. Food Safety Safeguarding: The measurement of Vomitoxin is of paramount importance to assure the safety of food products derived from grains. Human exposure to Vomitoxin-contaminated food items can lead to a range of adverse health consequences. This underscores the exigency of monitoring and curtailing its presence to adhere to food safety mandates and protect consumers from potential harm.
b. Livestock Health and Productivity: Within the ambit of animal husbandry, Vomitoxin poses a formidable threat to animal health and productivity. Quantifying Vomitoxin levels in animal feed is imperative to avert mycotoxin-linked maladies. This proactive approach helps mitigate economic losses due to compromised growth rates, decreased fertility, and immunosuppression, while also ensuring the overall welfare of livestock populations.
c. Crop Quality Assurance: Vomitoxin contamination has a pronounced negative impact on the quality of cereal grains, rendering them less marketable and utilitarian. The quantification of Vomitoxin empowers agrarians and grain handlers to make judicious decisions concerning grain suitability for diverse applications, encompassing human consumption and animal fodder. This ensures that grains meet the required quality standards for their intended use.
d. Regulatory Compliance: Diverse jurisdictions and regions worldwide have established stipulations concerning the allowable thresholds of Vomitoxin in comestibles and animal fodder. The measurement of Vomitoxin is indispensable for conformance with regulatory dictates, international trade, and ensuring that products adhere to established safety benchmarks. Regulatory compliance is fundamental in upholding food safety standards and protecting consumer interests.
e. Risk Mitigation: Routinely ascertaining Vomitoxin levels in grains furnishes a preemptive vantage point for detecting contamination issues in crops and victuals. This proactive approach facilitates the implementation of risk mitigation strategies, including mold control, prudent storage practices, and segregation of tainted grains. By intervening at an early stage, these measures prevent downstream complications in the supply chain stemming from mycotoxin presence.
In summation, the quantification of Vomitoxin is an indispensable scientific endeavor, playing a pivotal role in ensuring food safety, safeguarding animal health, assuring crop quality, facilitating regulatory compliance, and enabling effective risk mitigation within the agricultural and food sectors. By vigilantly monitoring and managing Vomitoxin contamination, stakeholders contribute to the preservation of human health, animal welfare, and the economic resilience of agricultural production systems.
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