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Anti-RARG monoclonal antibody
Pre-made anti-RARG monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RARG/RARG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T82146-Ab-1/ GM-Tg-hg-T82146-Ab-2 | Anti-Human RARG monoclonal antibody | Human |
| GM-Tg-rg-T82146-Ab-1/ GM-Tg-rg-T82146-Ab-2 | Anti-Rat RARG monoclonal antibody | Rat |
| GM-Tg-mg-T82146-Ab-1/ GM-Tg-mg-T82146-Ab-2 | Anti-Mouse RARG monoclonal antibody | Mouse |
| GM-Tg-cynog-T82146-Ab-1/ GM-Tg-cynog-T82146-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RARG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T82146-Ab-1/ GM-Tg-felg-T82146-Ab-2 | Anti-Feline RARG monoclonal antibody | Feline |
| GM-Tg-cang-T82146-Ab-1/ GM-Tg-cang-T82146-Ab-2 | Anti-Canine RARG monoclonal antibody | Canine |
| GM-Tg-bovg-T82146-Ab-1/ GM-Tg-bovg-T82146-Ab-2 | Anti-Bovine RARG monoclonal antibody | Bovine |
| GM-Tg-equg-T82146-Ab-1/ GM-Tg-equg-T82146-Ab-2 | Anti-Equine RARG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T82146-Ab-1/ GM-Tg-hg-T82146-Ab-2; GM-Tg-rg-T82146-Ab-1/ GM-Tg-rg-T82146-Ab-2; GM-Tg-mg-T82146-Ab-1/ GM-Tg-mg-T82146-Ab-2; GM-Tg-cynog-T82146-Ab-1/ GM-Tg-cynog-T82146-Ab-2; GM-Tg-felg-T82146-Ab-1/ GM-Tg-felg-T82146-Ab-2; GM-Tg-cang-T82146-Ab-1/ GM-Tg-cang-T82146-Ab-2; GM-Tg-bovg-T82146-Ab-1/ GM-Tg-bovg-T82146-Ab-2; GM-Tg-equg-T82146-Ab-1/ GM-Tg-equg-T82146-Ab-2 |
| Products Name | Anti-RARG monoclonal antibody |
| Format | mab |
| Target Name | RARG |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RARG monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T82146-Ag-1 | Recombinant multi-species RARG/ NR1B3/ RARC protein |
| ORF Viral Vector | vGMLP001553 | human RARG Lentivirus particle |
| ORF Viral Vector | pGMLP001553 | human RARG Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002565 | mouse Rarg Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002565 | mouse Rarg Lentivirus particle |
Target information
| Target ID | GM-T82146 |
| Target Name | RARG |
| Gene ID | 5916,19411,685072,699532,486508,101083275,540425,100062026 |
| Gene Symbol and Synonyms | NR1B3,RAR-gamma,RARC,RARD,RARG,RARgamma,RARgamma2 |
| Uniprot Accession | P13631 |
| Uniprot Entry Name | RARG_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000172819 |
| Target Classification | N/A |
The target: RARG, gene name: RARG, also named as NR1B3, RARC. This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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