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Anti-WNT7A monoclonal antibody
Anti-WNT7A antibody for FACS & in-vivo assay
Go to WNT7A/WNT7A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T73908-Ab-1/ GM-Tg-hg-T73908-Ab-2 | Anti-Human WNT7A monoclonal antibody | Human |
| GM-Tg-rg-T73908-Ab-1/ GM-Tg-rg-T73908-Ab-2 | Anti-Rat WNT7A monoclonal antibody | Rat |
| GM-Tg-mg-T73908-Ab-1/ GM-Tg-mg-T73908-Ab-2 | Anti-Mouse WNT7A monoclonal antibody | Mouse |
| GM-Tg-cynog-T73908-Ab-1/ GM-Tg-cynog-T73908-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WNT7A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T73908-Ab-1/ GM-Tg-felg-T73908-Ab-2 | Anti-Feline WNT7A monoclonal antibody | Feline |
| GM-Tg-cang-T73908-Ab-1/ GM-Tg-cang-T73908-Ab-2 | Anti-Canine WNT7A monoclonal antibody | Canine |
| GM-Tg-bovg-T73908-Ab-1/ GM-Tg-bovg-T73908-Ab-2 | Anti-Bovine WNT7A monoclonal antibody | Bovine |
| GM-Tg-equg-T73908-Ab-1/ GM-Tg-equg-T73908-Ab-2 | Anti-Equine WNT7A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T73908-Ab-1/ GM-Tg-hg-T73908-Ab-2; GM-Tg-rg-T73908-Ab-1/ GM-Tg-rg-T73908-Ab-2; GM-Tg-mg-T73908-Ab-1/ GM-Tg-mg-T73908-Ab-2; GM-Tg-cynog-T73908-Ab-1/ GM-Tg-cynog-T73908-Ab-2; GM-Tg-felg-T73908-Ab-1/ GM-Tg-felg-T73908-Ab-2; GM-Tg-cang-T73908-Ab-1/ GM-Tg-cang-T73908-Ab-2; GM-Tg-bovg-T73908-Ab-1/ GM-Tg-bovg-T73908-Ab-2; GM-Tg-equg-T73908-Ab-1/ GM-Tg-equg-T73908-Ab-2 |
| Products Name | Anti-WNT7A monoclonal antibody |
| Format | mab |
| Target Name | WNT7A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WNT7A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species WNT7A VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T73908-Ag-1 | wingless-type MMTV integration site family, member 7A (WNT7A) protein |
| ORF Viral Vector | vGMAP000321 | Human WNT7A Adenovirus particle |
| ORF Viral Vector | pGMLP000595 | human WNT7A Lentivirus plasmid |
| ORF Viral Vector | vGMLP000595 | human WNT7A Lentivirus particle |
| ORF Viral Vector | pGMAP000321 | Human WNT7A Adenovirus plasmid |
Target information
| Target ID | GM-T73908 |
| Target Name | WNT7A |
| Gene ID | 7476,22421,114850,693419,607180,101083664,533782 |
| Gene Symbol and Synonyms | px,tw,Wnt-7a,WNT7A |
| Uniprot Accession | O00755 |
| Uniprot Entry Name | WNT7A_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000154764 |
| Target Classification | N/A |
The target: WNT7A, gene name: WNT7A, also named as . This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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