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Anti-RPL15 monoclonal antibody
Pre-made anti-RPL15 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPL15/RPL15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T73230-Ab-1/ GM-Tg-hg-T73230-Ab-2 | Anti-Human RPL15 monoclonal antibody | Human |
| GM-Tg-rg-T73230-Ab-1/ GM-Tg-rg-T73230-Ab-2 | Anti-Rat RPL15 monoclonal antibody | Rat |
| GM-Tg-mg-T73230-Ab-1/ GM-Tg-mg-T73230-Ab-2 | Anti-Mouse RPL15 monoclonal antibody | Mouse |
| GM-Tg-cynog-T73230-Ab-1/ GM-Tg-cynog-T73230-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPL15 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T73230-Ab-1/ GM-Tg-felg-T73230-Ab-2 | Anti-Feline RPL15 monoclonal antibody | Feline |
| GM-Tg-cang-T73230-Ab-1/ GM-Tg-cang-T73230-Ab-2 | Anti-Canine RPL15 monoclonal antibody | Canine |
| GM-Tg-bovg-T73230-Ab-1/ GM-Tg-bovg-T73230-Ab-2 | Anti-Bovine RPL15 monoclonal antibody | Bovine |
| GM-Tg-equg-T73230-Ab-1/ GM-Tg-equg-T73230-Ab-2 | Anti-Equine RPL15 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T73230-Ab-1/ GM-Tg-hg-T73230-Ab-2; GM-Tg-rg-T73230-Ab-1/ GM-Tg-rg-T73230-Ab-2; GM-Tg-mg-T73230-Ab-1/ GM-Tg-mg-T73230-Ab-2; GM-Tg-cynog-T73230-Ab-1/ GM-Tg-cynog-T73230-Ab-2; GM-Tg-felg-T73230-Ab-1/ GM-Tg-felg-T73230-Ab-2; GM-Tg-cang-T73230-Ab-1/ GM-Tg-cang-T73230-Ab-2; GM-Tg-bovg-T73230-Ab-1/ GM-Tg-bovg-T73230-Ab-2; GM-Tg-equg-T73230-Ab-1/ GM-Tg-equg-T73230-Ab-2 |
| Products Name | Anti-RPL15 monoclonal antibody |
| Format | mab |
| Target Name | RPL15 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPL15 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T73230-Ag-1 | Recombinant multi-species RL15/ RPL15/ DBA12 protein |
| ORF Viral Vector | pGMLP003155 | human RPL15 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000358 | human RPL15 Lentivirus particle |
| ORF Viral Vector | pGMAP000374 | Human RPL15 Adenovirus plasmid |
| ORF Viral Vector | vGMLP003155 | human RPL15 Lentivirus particle |
| ORF Viral Vector | pGMLV000358 | human RPL15 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000374 | Human RPL15 Adenovirus particle |
| ORF Viral Vector | pGMLPm002238 | mouse Rpl15 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002238 | mouse Rpl15 Lentivirus particle |
Target information
| Target ID | GM-T73230 |
| Target Name | RPL15 |
| Gene ID | 6138,66480,245981,701255,477046,101083198,507151,100051688 |
| Gene Symbol and Synonyms | 2510008H07Rik,DBA12,EC45,eL15,L15,RPL10,RPL15,RPLY10,RPYL10 |
| Uniprot Accession | P61313,P61314,E2QXF3,Q5EAD6 |
| Uniprot Entry Name | RL15_HUMAN,RL15_RAT,RL15_CANLF,RL15_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000174748 |
| Target Classification | N/A |
The target: RPL15, gene name: RPL15, also named as DBA12, EC45, L15, RPL10, RPLY10, RPYL10. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L15E family of ribosomal proteins and a component of the 60S subunit. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Elevated expression of this gene has been observed in esophageal tumors and gastric cancer tissues, and deletion of this gene has been observed in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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