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Anti-ESRRA monoclonal antibody
Pre-made anti-ESRRA monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ESRRA/ESRRA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T72841-Ab-1/ GM-Tg-hg-T72841-Ab-2 | Anti-Human ESRRA monoclonal antibody | Human |
| GM-Tg-rg-T72841-Ab-1/ GM-Tg-rg-T72841-Ab-2 | Anti-Rat ESRRA monoclonal antibody | Rat |
| GM-Tg-mg-T72841-Ab-1/ GM-Tg-mg-T72841-Ab-2 | Anti-Mouse ESRRA monoclonal antibody | Mouse |
| GM-Tg-cynog-T72841-Ab-1/ GM-Tg-cynog-T72841-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ESRRA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T72841-Ab-1/ GM-Tg-felg-T72841-Ab-2 | Anti-Feline ESRRA monoclonal antibody | Feline |
| GM-Tg-cang-T72841-Ab-1/ GM-Tg-cang-T72841-Ab-2 | Anti-Canine ESRRA monoclonal antibody | Canine |
| GM-Tg-bovg-T72841-Ab-1/ GM-Tg-bovg-T72841-Ab-2 | Anti-Bovine ESRRA monoclonal antibody | Bovine |
| GM-Tg-equg-T72841-Ab-1/ GM-Tg-equg-T72841-Ab-2 | Anti-Equine ESRRA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T72841-Ab-1/ GM-Tg-hg-T72841-Ab-2; GM-Tg-rg-T72841-Ab-1/ GM-Tg-rg-T72841-Ab-2; GM-Tg-mg-T72841-Ab-1/ GM-Tg-mg-T72841-Ab-2; GM-Tg-cynog-T72841-Ab-1/ GM-Tg-cynog-T72841-Ab-2; GM-Tg-felg-T72841-Ab-1/ GM-Tg-felg-T72841-Ab-2; GM-Tg-cang-T72841-Ab-1/ GM-Tg-cang-T72841-Ab-2; GM-Tg-bovg-T72841-Ab-1/ GM-Tg-bovg-T72841-Ab-2; GM-Tg-equg-T72841-Ab-1/ GM-Tg-equg-T72841-Ab-2 |
| Products Name | Anti-ESRRA monoclonal antibody |
| Format | mab |
| Target Name | ESRRA |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ESRRA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T72841-Ag-1 | Recombinant multi-species ERR1/ ESRRA/ ERRa protein |
| ORF Viral Vector | pGMAD000107 | human ESRRA Adenovirus plasmid |
| ORF Viral Vector | vGMAD000107 | human ESRRA Adenovirus particle |
| ORF Viral Vector | pGMAAV000283 | house mouse Esrra AAV plasmid |
| ORF Viral Vector | pGMAAV000355 | house mouse Esrra AAV plasmid |
| ORF Viral Vector | pGMLPm004325 | mouse Esrra Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000283 | house mouse Esrra AAV particle |
| ORF Viral Vector | vGMAAV000355 | house mouse Esrra AAV particle |
| ORF Viral Vector | vGMLPm004325 | mouse Esrra Lentivirus particle |
Target information
| Target ID | GM-T72841 |
| Target Name | ESRRA |
| Gene ID | 2101,26379,293701,722085,403169,101099657,507834,100055615 |
| Gene Symbol and Synonyms | ERR1,ERRa,ERRalpha,Errra,ESRL1,ESRRA,Estrra,NR3B1 |
| Uniprot Accession | P11474,Q5QJV7,Q6QMY5 |
| Uniprot Entry Name | ERR1_HUMAN,ERR1_RAT,ERR1_CANLF |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000173153 |
| Target Classification | Nuclear Receptors |
The target: ESRRA, gene name: ESRRA, also named as ERR1, ERRa, ERRalpha, ESRL1, NR3B1. The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq, Jun 2019].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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