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Anti-JUN monoclonal antibody
Pre-made anti-JUN monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to JUN/JUN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T69085-Ab-1/ GM-Tg-hg-T69085-Ab-2 | Anti-Human JUN monoclonal antibody | Human |
| GM-Tg-rg-T69085-Ab-1/ GM-Tg-rg-T69085-Ab-2 | Anti-Rat JUN monoclonal antibody | Rat |
| GM-Tg-mg-T69085-Ab-1/ GM-Tg-mg-T69085-Ab-2 | Anti-Mouse JUN monoclonal antibody | Mouse |
| GM-Tg-cynog-T69085-Ab-1/ GM-Tg-cynog-T69085-Ab-2 | Anti-Cynomolgus/ Rhesus macaque JUN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T69085-Ab-1/ GM-Tg-felg-T69085-Ab-2 | Anti-Feline JUN monoclonal antibody | Feline |
| GM-Tg-cang-T69085-Ab-1/ GM-Tg-cang-T69085-Ab-2 | Anti-Canine JUN monoclonal antibody | Canine |
| GM-Tg-bovg-T69085-Ab-1/ GM-Tg-bovg-T69085-Ab-2 | Anti-Bovine JUN monoclonal antibody | Bovine |
| GM-Tg-equg-T69085-Ab-1/ GM-Tg-equg-T69085-Ab-2 | Anti-Equine JUN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T69085-Ab-1/ GM-Tg-hg-T69085-Ab-2; GM-Tg-rg-T69085-Ab-1/ GM-Tg-rg-T69085-Ab-2; GM-Tg-mg-T69085-Ab-1/ GM-Tg-mg-T69085-Ab-2; GM-Tg-cynog-T69085-Ab-1/ GM-Tg-cynog-T69085-Ab-2; GM-Tg-felg-T69085-Ab-1/ GM-Tg-felg-T69085-Ab-2; GM-Tg-cang-T69085-Ab-1/ GM-Tg-cang-T69085-Ab-2; GM-Tg-bovg-T69085-Ab-1/ GM-Tg-bovg-T69085-Ab-2; GM-Tg-equg-T69085-Ab-1/ GM-Tg-equg-T69085-Ab-2 |
| Products Name | Anti-JUN monoclonal antibody |
| Format | mab |
| Target Name | JUN |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-JUN monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T69085-Ag-1 | Recombinant multi-species JUN/ AP-1/ AP1 protein |
| ORF Viral Vector | pGMAP000535 | Human JUN Adenovirus plasmid |
| ORF Viral Vector | vGMAP000535 | Human JUN Adenovirus particle |
| ORF Viral Vector | pGMLV000295 | human JUN Lentivirus plasmid |
| ORF Viral Vector | vGMAD000140 | human JUN Adenovirus particle |
| ORF Viral Vector | vGMLV000295 | human JUN Lentivirus particle |
| ORF Viral Vector | pGMAD000140 | human JUN Adenovirus plasmid |
| ORF Viral Vector | pGMAAV000054 | mouse Jun AAV plasmid |
| ORF Viral Vector | vGMAAV000054 | mouse Jun AAV particle |
Target information
| Target ID | GM-T69085 |
| Target Name | JUN |
| Gene ID | 3725,16476,24516,716452,609429,101097261,280831,100067469 |
| Gene Symbol and Synonyms | AP-1,AP1,c-Jun,cJUN,JUN,Junc,p39 |
| Uniprot Accession | P05412,P17325,O77627 |
| Uniprot Entry Name | JUN_HUMAN,JUN_RAT,JUN_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000177606 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: JUN, gene name: JUN, also named as AP-1, AP1, c-Jun, p39. This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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