- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SUV39H1 monoclonal antibody
Pre-made anti-SUV39H1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SUV39H1/SUV39H1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T39519-Ab-1/ GM-Tg-hg-T39519-Ab-2 | Anti-Human SUV39H1 monoclonal antibody | Human |
| GM-Tg-rg-T39519-Ab-1/ GM-Tg-rg-T39519-Ab-2 | Anti-Rat SUV39H1 monoclonal antibody | Rat |
| GM-Tg-mg-T39519-Ab-1/ GM-Tg-mg-T39519-Ab-2 | Anti-Mouse SUV39H1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T39519-Ab-1/ GM-Tg-cynog-T39519-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SUV39H1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T39519-Ab-1/ GM-Tg-felg-T39519-Ab-2 | Anti-Feline SUV39H1 monoclonal antibody | Feline |
| GM-Tg-cang-T39519-Ab-1/ GM-Tg-cang-T39519-Ab-2 | Anti-Canine SUV39H1 monoclonal antibody | Canine |
| GM-Tg-bovg-T39519-Ab-1/ GM-Tg-bovg-T39519-Ab-2 | Anti-Bovine SUV39H1 monoclonal antibody | Bovine |
| GM-Tg-equg-T39519-Ab-1/ GM-Tg-equg-T39519-Ab-2 | Anti-Equine SUV39H1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T39519-Ab-1/ GM-Tg-hg-T39519-Ab-2; GM-Tg-rg-T39519-Ab-1/ GM-Tg-rg-T39519-Ab-2; GM-Tg-mg-T39519-Ab-1/ GM-Tg-mg-T39519-Ab-2; GM-Tg-cynog-T39519-Ab-1/ GM-Tg-cynog-T39519-Ab-2; GM-Tg-felg-T39519-Ab-1/ GM-Tg-felg-T39519-Ab-2; GM-Tg-cang-T39519-Ab-1/ GM-Tg-cang-T39519-Ab-2; GM-Tg-bovg-T39519-Ab-1/ GM-Tg-bovg-T39519-Ab-2; GM-Tg-equg-T39519-Ab-1/ GM-Tg-equg-T39519-Ab-2 |
| Products Name | Anti-SUV39H1 monoclonal antibody |
| Format | mab |
| Target Name | SUV39H1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SUV39H1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T39519-Ag-1 | Recombinant multi-species SUV91/ SUV39H1/ H3-K9-HMTase 1 protein |
| ORF Viral Vector | pGMLP000110 | human SUV39H1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000110 | human SUV39H1 Lentivirus particle |
| ORF Viral Vector | pGMLPm002105 | mouse Suv39h1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002105 | mouse Suv39h1 Lentivirus particle |
Target information
| Target ID | GM-T39519 |
| Target Name | SUV39H1 |
| Gene ID | 6839,20937,302553,711040,491868,101083571,523047,100062108 |
| Gene Symbol and Synonyms | DXHXS7466e,H3-K9-HMTase 1,KMT1A,MG44,mIS6,RGD1565028,SUV39H,SUV39H1,Suv39h1l1 |
| Uniprot Accession | O43463,Q2NL30 |
| Uniprot Entry Name | SUV91_HUMAN,SUV91_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000101945 |
| Target Classification | N/A |
The target: SUV39H1, gene name: SUV39H1, also named as H3-K9-HMTase 1, KMT1A, MG44, SUV39H. This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
