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Anti-TGFA/ TFGA monoclonal antibody
Anti-TGFA/ TFGA antibody for FACS & in-vivo assay
Go to TGFA/TGFA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T00033-Ab-1/ GM-Tg-hg-T00033-Ab-2 | Anti-Human TGFA monoclonal antibody | Human |
| GM-Tg-rg-T00033-Ab-1/ GM-Tg-rg-T00033-Ab-2 | Anti-Rat TGFA monoclonal antibody | Rat |
| GM-Tg-mg-T00033-Ab-1/ GM-Tg-mg-T00033-Ab-2 | Anti-Mouse TGFA monoclonal antibody | Mouse |
| GM-Tg-cynog-T00033-Ab-1/ GM-Tg-cynog-T00033-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TGFA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T00033-Ab-1/ GM-Tg-felg-T00033-Ab-2 | Anti-Feline TGFA monoclonal antibody | Feline |
| GM-Tg-cang-T00033-Ab-1/ GM-Tg-cang-T00033-Ab-2 | Anti-Canine TGFA monoclonal antibody | Canine |
| GM-Tg-bovg-T00033-Ab-1/ GM-Tg-bovg-T00033-Ab-2 | Anti-Bovine TGFA monoclonal antibody | Bovine |
| GM-Tg-equg-T00033-Ab-1/ GM-Tg-equg-T00033-Ab-2 | Anti-Equine TGFA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T00033-Ab-1/ GM-Tg-hg-T00033-Ab-2; GM-Tg-rg-T00033-Ab-1/ GM-Tg-rg-T00033-Ab-2; GM-Tg-mg-T00033-Ab-1/ GM-Tg-mg-T00033-Ab-2; GM-Tg-cynog-T00033-Ab-1/ GM-Tg-cynog-T00033-Ab-2; GM-Tg-felg-T00033-Ab-1/ GM-Tg-felg-T00033-Ab-2; GM-Tg-cang-T00033-Ab-1/ GM-Tg-cang-T00033-Ab-2; GM-Tg-bovg-T00033-Ab-1/ GM-Tg-bovg-T00033-Ab-2; GM-Tg-equg-T00033-Ab-1/ GM-Tg-equg-T00033-Ab-2 |
| Products Name | Anti-TGFA monoclonal antibody |
| Format | mab |
| Target Name | TGFA |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TGFA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species TGFA/ TFGA VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T00033-Ag-1 | transforming growth factor, alpha (TGFA) protein |
| ORF Viral Vector | vGMLP000405 | human TGFA Lentivirus particle |
| ORF Viral Vector | vGMAP000120 | Human TGFA Adenovirus particle |
| ORF Viral Vector | pGMAP000120 | Human TGFA Adenovirus plasmid |
| ORF Viral Vector | pGMLP000405 | human TGFA Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000609 | mouse Tgfa Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000609 | mouse Tgfa Lentivirus particle |
Target information
| Target ID | GM-T00033 |
| Target Name | TGFA |
| Gene ID | 7039,21802,24827,613031,403431,101094921,540388,100060423 |
| Gene Symbol and Synonyms | RATTGFAA,TFGA,TGF alpha,TGFA,TGFAA,wa-1,wa1 |
| Uniprot Accession | P01135,P01134,P55244 |
| Uniprot Entry Name | TGFA_HUMAN,TGFA_MACMU,TGFA_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | cancer patients |
| Gene Ensembl | ENSG00000163235 |
| Target Classification | N/A |
The target: TGFA, gene name: TGFA, also named as TFGA. This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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