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Anti-UCN3/ SCP/ SPC functional antibody
Anti-UCN3/ SCP/ SPC functional antibody for cell culture, ELISA & in-vivo assay
Go to UCN3/UCN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1357-Ab-1/ GM-Tg-hg-SE1357-Ab-2 | Anti-Human UCN3 monoclonal antibody | Human |
| GM-Tg-rg-SE1357-Ab-1/ GM-Tg-rg-SE1357-Ab-2 | Anti-Rat UCN3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1357-Ab-1/ GM-Tg-mg-SE1357-Ab-2 | Anti-Mouse UCN3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1357-Ab-1/ GM-Tg-cynog-SE1357-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UCN3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1357-Ab-1/ GM-Tg-felg-SE1357-Ab-2 | Anti-Feline UCN3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1357-Ab-1/ GM-Tg-cang-SE1357-Ab-2 | Anti-Canine UCN3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1357-Ab-1/ GM-Tg-bovg-SE1357-Ab-2 | Anti-Bovine UCN3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1357-Ab-1/ GM-Tg-equg-SE1357-Ab-2 | Anti-Equine UCN3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1357-Ab-1/ GM-Tg-hg-SE1357-Ab-2; GM-Tg-rg-SE1357-Ab-1/ GM-Tg-rg-SE1357-Ab-2; GM-Tg-mg-SE1357-Ab-1/ GM-Tg-mg-SE1357-Ab-2; GM-Tg-cynog-SE1357-Ab-1/ GM-Tg-cynog-SE1357-Ab-2; GM-Tg-felg-SE1357-Ab-1/ GM-Tg-felg-SE1357-Ab-2; GM-Tg-cang-SE1357-Ab-1/ GM-Tg-cang-SE1357-Ab-2; GM-Tg-bovg-SE1357-Ab-1/ GM-Tg-bovg-SE1357-Ab-2; GM-Tg-equg-SE1357-Ab-1/ GM-Tg-equg-SE1357-Ab-2 |
| Products Name | Anti-UCN3 monoclonal antibody |
| Format | mab |
| Target Name | UCN3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UCN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1357-Ag-1 | Recombinant multi-species UCN3/ SCP/ SPC protein |
| ORF Viral Vector | pGMLP004588 | human Ucn3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004588 | human Ucn3 Lentivirus particle |
| ORF Viral Vector | pGMLPm000234 | mouse Ucn3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000234 | mouse Ucn3 Lentivirus particle |
Target information
| Target ID | GM-SE1357 |
| Target Name | UCN3 |
| Gene ID | 114131,83428,498791,711921,100856134,101098548,751573,100057172 |
| Gene Symbol and Synonyms | RGD1562213,SCP,SPC,ucn III,UCN3,UCNIII |
| Uniprot Accession | Q969E3,Q1RMJ9 |
| Uniprot Entry Name | UCN3_HUMAN,UCN3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000178473 |
| Target Classification | N/A |
The target: UCN3, gene name: UCN3, also named as SCP, SPC, UCNIII. This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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