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Anti-ALR/ GFER/ ERV1 functional antibody
Anti-ALR/ GFER/ ERV1 functional antibody for cell culture, ELISA & in-vivo assay
Go to GFER/GFER products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0943-Ab-1/ GM-Tg-hg-SE0943-Ab-2 | Anti-Human GFER monoclonal antibody | Human |
| GM-Tg-rg-SE0943-Ab-1/ GM-Tg-rg-SE0943-Ab-2 | Anti-Rat GFER monoclonal antibody | Rat |
| GM-Tg-mg-SE0943-Ab-1/ GM-Tg-mg-SE0943-Ab-2 | Anti-Mouse GFER monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0943-Ab-1/ GM-Tg-cynog-SE0943-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GFER monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0943-Ab-1/ GM-Tg-felg-SE0943-Ab-2 | Anti-Feline GFER monoclonal antibody | Feline |
| GM-Tg-cang-SE0943-Ab-1/ GM-Tg-cang-SE0943-Ab-2 | Anti-Canine GFER monoclonal antibody | Canine |
| GM-Tg-bovg-SE0943-Ab-1/ GM-Tg-bovg-SE0943-Ab-2 | Anti-Bovine GFER monoclonal antibody | Bovine |
| GM-Tg-equg-SE0943-Ab-1/ GM-Tg-equg-SE0943-Ab-2 | Anti-Equine GFER monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0943-Ab-1/ GM-Tg-hg-SE0943-Ab-2; GM-Tg-rg-SE0943-Ab-1/ GM-Tg-rg-SE0943-Ab-2; GM-Tg-mg-SE0943-Ab-1/ GM-Tg-mg-SE0943-Ab-2; GM-Tg-cynog-SE0943-Ab-1/ GM-Tg-cynog-SE0943-Ab-2; GM-Tg-felg-SE0943-Ab-1/ GM-Tg-felg-SE0943-Ab-2; GM-Tg-cang-SE0943-Ab-1/ GM-Tg-cang-SE0943-Ab-2; GM-Tg-bovg-SE0943-Ab-1/ GM-Tg-bovg-SE0943-Ab-2; GM-Tg-equg-SE0943-Ab-1/ GM-Tg-equg-SE0943-Ab-2 |
| Products Name | Anti-GFER monoclonal antibody |
| Format | mab |
| Target Name | GFER |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GFER benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0943-Ag-1 | Recombinant multi-species ALR/ GFER/ ERV1 protein |
| ORF Viral Vector | vGMLP003164 | human GFER Lentivirus particle |
| ORF Viral Vector | pGMLV000509 | human GFER Lentivirus plasmid |
| ORF Viral Vector | pGMLP003164 | human GFER Lentivirus plasmid |
| ORF Viral Vector | vGMLV000509 | human GFER Lentivirus particle |
| ORF Viral Vector | pGMLPm000588 | mouse Gfer Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000588 | mouse Gfer Lentivirus particle |
Target information
| Target ID | GM-SE0943 |
| Target Name | GFER |
| Gene ID | 2671,11692,27100,694203,479885,101082968,618423,100065617 |
| Gene Symbol and Synonyms | ALR,ERV1,GFER,HERV1,HPO,HPO1,HPO2,HSS,MMCHD,MPMCD |
| Uniprot Accession | P55789,Q63042 |
| Uniprot Entry Name | ALR_HUMAN,ALR_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000127554 |
| Target Classification | N/A |
The target: GFER, gene name: GFER, also named as ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS. The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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