Anti-FGF9/ FGF-9/ GAF functional antibody
Anti-FGF9/ FGF-9/ GAF functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0923-Ab-1/ GM-Tg-hg-SE0923-Ab-2 | Anti-Human FGF9 monoclonal antibody | Human |
GM-Tg-rg-SE0923-Ab-1/ GM-Tg-rg-SE0923-Ab-2 | Anti-Rat FGF9 monoclonal antibody | Rat |
GM-Tg-mg-SE0923-Ab-1/ GM-Tg-mg-SE0923-Ab-2 | Anti-Mouse FGF9 monoclonal antibody | Mouse |
GM-Tg-cynog-SE0923-Ab-1/ GM-Tg-cynog-SE0923-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0923-Ab-1/ GM-Tg-felg-SE0923-Ab-2 | Anti-Feline FGF9 monoclonal antibody | Feline |
GM-Tg-cang-SE0923-Ab-1/ GM-Tg-cang-SE0923-Ab-2 | Anti-Canine FGF9 monoclonal antibody | Canine |
GM-Tg-bovg-SE0923-Ab-1/ GM-Tg-bovg-SE0923-Ab-2 | Anti-Bovine FGF9 monoclonal antibody | Bovine |
GM-Tg-equg-SE0923-Ab-1/ GM-Tg-equg-SE0923-Ab-2 | Anti-Equine FGF9 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE0923-Ab-1/ GM-Tg-hg-SE0923-Ab-2; GM-Tg-rg-SE0923-Ab-1/ GM-Tg-rg-SE0923-Ab-2; GM-Tg-mg-SE0923-Ab-1/ GM-Tg-mg-SE0923-Ab-2; GM-Tg-cynog-SE0923-Ab-1/ GM-Tg-cynog-SE0923-Ab-2; GM-Tg-felg-SE0923-Ab-1/ GM-Tg-felg-SE0923-Ab-2; GM-Tg-cang-SE0923-Ab-1/ GM-Tg-cang-SE0923-Ab-2; GM-Tg-bovg-SE0923-Ab-1/ GM-Tg-bovg-SE0923-Ab-2; GM-Tg-equg-SE0923-Ab-1/ GM-Tg-equg-SE0923-Ab-2 |
Products Name | Anti-FGF9 monoclonal antibody |
Format | mab |
Target Name | FGF9 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-FGF9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE0923-Ag-1 | Recombinant multi-species FGF9/ FGF-9/ GAF protein |
Cytokine | GM-Tg-g-SE0923-Ag-1 | fibroblast growth factor 9 (glia-activating factor) (FGF9) protein |
ORF Viral Vector | pGMLP003449 | human FGF9 Lentivirus plasmid |
ORF Viral Vector | vGMLP003449 | human FGF9 Lentivirus particle |
ORF Viral Vector | pGMAD000626 | goat FGF9 Adenovirus plasmid |
ORF Viral Vector | pGMLPm000372 | mouse Fgf9 Lentivirus plasmid |
ORF Viral Vector | vGMAD000626 | goat FGF9 Adenovirus particle |
ORF Viral Vector | vGMLPm000372 | mouse Fgf9 Lentivirus particle |
Target information
Target ID | GM-SE0923 |
Target Name | FGF9 |
Gene ID | 2254,14180,25444,721324,477340,101084335,613731,100050353 |
Gene Symbol and Synonyms | Eks,FGF-9,Fgf4b,FGF9,GAF,HBFG-9,HBGF-9,SYNS3 |
Uniprot Accession | P31371,P36364 |
Uniprot Entry Name | FGF9_HUMAN,FGF9_RAT |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Cytokine Target |
Disease | N/A |
Gene Ensembl | ENSG00000102678 |
Target Classification | N/A |
The target: FGF9, gene name: FGF9, also named as FGF-9, GAF, HBFG-9, HBGF-9, SYNS3. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.